Salvinelli Fabrizio, Bonifacio Francesca, Greco Fabio, Cavicchioni Giulio, Frari Valeria, Pierri Michelangelo, Trivelli Maurizio, Iacoangeli Maurizio
Department of Otorhinolaryngology, Fondazione Policlinico Campus Biomedico, Rome.
Research Unit of Otorhinolaryngology, Campus Biomedico Universty, Rome.
Surg Neurol Int. 2022 Sep 16;13:418. doi: 10.25259/SNI_187_2022. eCollection 2022.
The present article aims to introduce the endolymphatic duct and sac decompression technique (DASD) and to give a spotlight on its benefits in Ménière's disease (MD) treatment.
Eighty-two patients with intractable MD which met the inclusion criteria were recruited and underwent DASD. This technique allows a meningeal decompression of the duct and the sac from the posterior cranial fossa to the labyrinthine block. The authors considered as main outcomes, the change of the dizziness handicap inventory (DHI) results, with the evaluations of the three sub-scales (Functional scale, Physical scale, and Emotional scale); ear fullness and tinnitus change on the perceptions of the patient; and hearing stage with four-Pure Tone Average (500 hz-1000 hz-2000 hz-4000 hz). The differences between the preoperative and the postoperative score were evaluated. A comparison with the literature was conducted.
After a 14-month follow-up, patients that underwent DASD reported a remarkable improvement of the symptoms in all three functional scales, confirmed by the total DHI. The difference between preoperative and postoperative scores is statistically significant. The data describe an ear fullness and tinnitus improvement. The multi-frequency tonal average before and after the surgery does not suggest a worsening of the value for any of 82 patients.
The modification of sac surgery includes the endolymphatic duct in the decompression area allowing inner ear functional improvement, vertigo control, ear fullness improvement with minimal risk of facial nerve paralysis, and hearing loss. DASD is an improved old surgical technique.
本文旨在介绍内淋巴管和内淋巴囊减压技术(DASD),并重点阐述其在梅尼埃病(MD)治疗中的益处。
招募了82例符合纳入标准的难治性MD患者,并对其进行了DASD手术。该技术可从后颅窝至迷路阻滞对内淋巴管和内淋巴囊进行脑膜减压。作者将头晕残障量表(DHI)结果的变化作为主要结局指标,评估三个子量表(功能量表、身体量表和情感量表);患者对耳胀满感和耳鸣变化的感知;以及采用四频率纯音平均听阈(500赫兹 - 1000赫兹 - 2000赫兹 - 4000赫兹)评估听力阶段。评估术前和术后评分的差异,并与文献进行比较。
经过14个月的随访,接受DASD手术的患者在所有三个功能量表上均报告症状有显著改善,总DHI证实了这一点。术前和术后评分的差异具有统计学意义。数据表明耳胀满感和耳鸣有所改善。手术前后的多频率音调平均值并未显示82例患者中的任何一例数值恶化。
囊手术的改进包括在内淋巴囊减压区域纳入内淋巴管,可改善内耳功能、控制眩晕、改善耳胀满感,且面神经麻痹和听力损失风险极小。DASD是一种改良的传统手术技术。