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微血管减压术后半面痉挛患者面神经根部出口区切迹与远期疗效的相关性分析:一项前瞻性研究

Analysing Correlation Between the Facial Nerve Notch at the Root Exit Zone and Long-term Effect in Patients with Hemifacial Spasm After Microvascular Decompression: A Prospective Study.

作者信息

Fang Li, Haidong Song, Jianfeng Liang, Ruen Liu

机构信息

Department of Neurosurgery, Peking University People's Hospital, Peking University; Trauma Medical Center, Peking University People's Hospital, Beijing, People's Republic of China.

Department of Neurosurgery, Peking University People's Hospital, Peking University, Beijing, People's Republic of China.

出版信息

Neurol India. 2022 Sep-Oct;70(5):1819-1823. doi: 10.4103/0028-3886.359293.

Abstract

BACKGROUND

Microvascular decompression (MVD) has become widely accepted for hemifacial spasm (HFS). The significance of facial nerve notch (FNN) for the outcome after MVD is still unknown.

OBJECTIVE

To investigate the correlative analysis between the FNN at the root exit zone (REZ) and the curative effect of MVD for HFS.

METHOD

A prospective study was performed, which included 232 patients with Cohen score ≥2 who had undergone MVD. The patients were divided into two groups: the group with facial nerve notch (FNN) and the group without FNN, according to whether there is FNN caused by the offending vessels during the MVD operation. All the patients were followed up for 24 months.

RESULTS

The group with FNN caused by offending vessels at the REZ area was confirmed in 119 patients, of which 117 patients were immediately cured and two patients received partial relief on the 1 day of postoperation. The group without FNN at the REZ area was confirmed in 113 patients, of which 43 patients were immediately completely cured while 70 patients were not immediately completely cured after MVD operation. After 24 months of follow-up, 119 patients with FNN were all completely cured, 71 patients without FNN were completely cured, and 42 patients without FNN were not completely cured. Multivariate logistic regression analysis shows that compared with without FNN group, the FNN group had statistical significance for the clinical results both on the-1 -day (P < 0.01) and 2 years of follow-up (P < 0.05) after MVD operation.

CONCLUSIONS

FNN is an important reference factor to evaluate both the short-term and long-term curative effect of microvascular decompression for hemifacial spasm. The postoperative effect of patients with FNN is much better than that of patients without FNN.

摘要

背景

微血管减压术(MVD)已被广泛应用于治疗面肌痉挛(HFS)。面神经切迹(FNN)对MVD术后疗效的意义尚不清楚。

目的

探讨面神经根部出口区(REZ)的FNN与MVD治疗HFS疗效之间的相关性分析。

方法

进行一项前瞻性研究,纳入232例Cohen评分≥2且接受过MVD的患者。根据MVD手术中是否存在责任血管导致的FNN,将患者分为两组:有FNN组和无FNN组。所有患者均随访24个月。

结果

REZ区因责任血管导致FNN的患者有119例,其中117例术后1天立即治愈,2例部分缓解。REZ区无FNN的患者有113例,其中43例MVD术后立即完全治愈,70例未立即完全治愈。随访24个月后,119例有FNN的患者均完全治愈,71例无FNN的患者完全治愈,42例无FNN的患者未完全治愈。多因素logistic回归分析显示,与无FNN组相比,FNN组在MVD术后1天(P<0.01)和随访2年(P<0.05)时的临床结果具有统计学意义。

结论

FNN是评估微血管减压术治疗面肌痉挛短期和长期疗效的重要参考因素。有FNN的患者术后效果明显优于无FNN的患者。

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