Department of Neurosurgery, Adiyaman University Education and Research Hospital, Adiyaman, Turkey.
Department of cardiology, Adiyaman University Education and Research Hospital, Adiyaman, Turkey.
BMC Cardiovasc Disord. 2022 Nov 10;22(1):477. doi: 10.1186/s12872-022-02924-y.
Various electrocardiographic (ECG) changes occur after subarachnoid hemorrhage (SAH). Prolonged QT and corrected QT (QTc) intervals are notable changes. QT, QTc, T peak-to-end T(p-e) intervals, and Tp-e/QTc ratio are used as ventricular arrhythmia indices. In recent publications, the cardiac electrophysiological balance index (ICEB), which provides more information than other ECG parameters (QT, QTc, etc.), is recommended in predicting the risk of ventricular arrhythmia. This study aims to assess ICEB in aneurysmal SAH patients.
The study included 50 patients diagnosed with aneurysmal SAH and 50 patients diagnosed with hypertension without end-organ damage as the control group. All patients' Fisher scores and Glasgow Coma Scale (GCS) scores were recorded. Both groups were given 12-lead ECGs. QT, QTc, Tp-e intervals, QRS duration, ICEB (QT/QRS), ICEBc (QTc/QRS), and T(p-e)/QTc values were calculated and analyzed between groups.
Compared to the control group; QT (426,64 ± 14,62 vs. 348,84 ± 12,24 ms, p < 0,001), QTc (456,24 ± 28,84 vs. 392,48 ± 14,36 ms, p < 0,001), Tp-e (84,32 ± 3,46 vs. 70,12 ± 3,12, p < 0,001), Tp-e/QTc (0,185 ± 0,08 vs. 0,178 ± 0,02, p < 0,001), ICEB (4,53 ± 0,78 vs. 3,74 ± 0,28, p < 0,001) and ICEBc (4,86 ± 0,86 vs. 4,21 ± 0,24, p < 0,001) were significantly higher in patients with aneurysmal SAH. QT, QTc and Tp-e interval, Tp-e/QTc ratio, ICEB (QT/QRS) and ICEBc (QTc/QRS) were positively correlated with the Fisher score and were negatively correlated with the GCS. According to linear regression analyses, the ICEBc (QTc/QRS) found to be independently associated with the Fisher score.
The values of the ICEB and ICEBc were significantly increased in patients with aneurysmal SAH. The severity of SAH was positively correlated with the ICEB and ICEBc. The ICEBc (QTc/QRS) independently associated with the Fisher score. This may that SAH suggest may predispose to malignant ventricular arrhythmias.
蛛网膜下腔出血(SAH)后会发生各种心电图(ECG)变化。QT 间期和校正 QT(QTc)间期延长是显著变化。QT、QTc、Tp-e 间期、Tp-e/QTc 比值等可作为室性心律失常指标。在最近的出版物中,心脏电生理平衡指数(ICEB)比其他 ECG 参数(QT、QTc 等)提供更多信息,被推荐用于预测室性心律失常的风险。本研究旨在评估动脉瘤性 SAH 患者的 ICEB。
该研究纳入了 50 例诊断为动脉瘤性 SAH 的患者和 50 例诊断为高血压但无终末器官损害的患者作为对照组。记录所有患者的 Fisher 评分和格拉斯哥昏迷量表(GCS)评分。两组均进行 12 导联心电图检查。计算并分析组间 QT、QTc、Tp-e 间期、QRS 持续时间、ICEB(QT/QRS)、ICEBc(QTc/QRS)和 T(p-e)/QTc 值。
与对照组相比;QT(426.64±14.62 与 348.84±12.24 ms,p<0.001)、QTc(456.24±28.84 与 392.48±14.36 ms,p<0.001)、Tp-e(84.32±3.46 与 70.12±3.12,p<0.001)、Tp-e/QTc(0.185±0.08 与 0.178±0.02,p<0.001)、ICEB(4.53±0.78 与 3.74±0.28,p<0.001)和 ICEBc(4.86±0.86 与 4.21±0.24,p<0.001)在动脉瘤性 SAH 患者中明显升高。QT、QTc 和 Tp-e 间期、Tp-e/QTc 比值、ICEB(QT/QRS)和 ICEBc(QTc/QRS)与 Fisher 评分呈正相关,与 GCS 呈负相关。根据线性回归分析,发现 ICEBc(QTc/QRS)与 Fisher 评分独立相关。
动脉瘤性 SAH 患者的 ICEB 和 ICEBc 值明显升高。SAH 的严重程度与 ICEB 和 ICEBc 呈正相关。ICEBc(QTc/QRS)与 Fisher 评分独立相关。这可能表明 SAH 可能容易发生恶性室性心律失常。