Suter P M, Demottaz V, Hemmer M
Herz. 1978 Jun;3(3):198-205.
In 11 patients requiring coronary bypass surgery during extracorporeal circulation we measured pulmonary function and hemodynamic variables before surgery and during the postoperative period. None of the patients presented with pulmonary hypertension or cardiac failure. Cardiac surgery with extracorporeal circulation caused an important decrease in functional residual capacity (-60%) and in arterial oxygenation (-44%). In the immediate postoperative period, the addition of a positive end-expiratory pressure (PEEP) to mechanical ventilation produced an increase in functional residual capacity and in arterial oxygen tension, and a slight decrease in cardiac output. In contrast to the results obtained in children after cardiac surgery and in adults presenting with viral pneumonia or respiratory distress after polytrauma or surgery, continuous positive airway pressure during spontaneous breathing (CPAP) did not improve pulmonary gas exchange in our patients, despite the significant increase in functional residual capacity produced. This suggests that CPAP did not cause recruitement of atelectatic areas or that this effect was offset by a parallel overdistension of gas exchange units.
在11例需要在体外循环期间进行冠状动脉搭桥手术的患者中,我们在手术前和术后测量了肺功能和血流动力学变量。所有患者均未出现肺动脉高压或心力衰竭。体外循环心脏手术导致功能残气量显著降低(-60%)和动脉氧合显著降低(-44%)。在术后即刻,机械通气时加用呼气末正压(PEEP)可使功能残气量和动脉氧分压增加,心输出量略有降低。与心脏手术后儿童以及多发伤或手术后出现病毒性肺炎或呼吸窘迫的成人所获得的结果不同,尽管功能残气量显著增加,但我们的患者在自主呼吸时持续气道正压通气(CPAP)并未改善肺气体交换。这表明CPAP并未导致肺不张区域复张,或者这种作用被气体交换单位的同时过度扩张所抵消。