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克罗恩病术后复发的预防与监测

Post-operative prevention and monitoring of Crohn's disease recurrence.

作者信息

Lee Kate E, Cantrell Sarah, Shen Bo, Faye Adam S

机构信息

Department of Medicine, Duke University Medical Center, Durham, NC, USA.

Duke University Medical Center Library & Archives, Duke University School of Medicine, Durham, NC, USA.

出版信息

Gastroenterol Rep (Oxf). 2022 Nov 16;10:goac070. doi: 10.1093/gastro/goac070. eCollection 2022.

Abstract

Crohn's disease (CD) and ulcerative colitis (UC) are relapsing and remitting chronic inflammatory diseases of the gastrointestinal tract. Although surgery for UC can provide a cure, surgery for CD is rarely curative. In the past few decades, research has identified risk factors for postsurgical CD recurrence, enabling patient risk stratification to guide monitoring and prophylactic treatment to prevent CD recurrence. A MEDLINE literature review identified articles regarding post-operative monitoring of CD recurrence after resection surgery. In this review, we discuss the evidence on risk factors for post-operative CD recurrence as well as suggestions on post-operative management.

摘要

克罗恩病(CD)和溃疡性结肠炎(UC)是胃肠道的复发性和缓解性慢性炎症性疾病。虽然UC手术可实现治愈,但CD手术很少能治愈。在过去几十年中,研究已确定了CD术后复发的风险因素,从而能够对患者进行风险分层,以指导监测和预防性治疗,防止CD复发。一项MEDLINE文献综述确定了关于切除术后CD复发的术后监测的文章。在本综述中,我们讨论了CD术后复发风险因素的证据以及术后管理建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9bc/9667961/9831db71b6c5/goac070f1.jpg

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