Waters Kristin
Assistant Clinical Professor, University of Connecticut, Storrs, Connecticut,
Ment Health Clin. 2022 Nov 3;12(5):309-319. doi: 10.9740/mhc.2022.10.309. eCollection 2022 Oct.
Whereas MDD is characterized in part by changes in mood, other symptoms can also cause significant impairment, including sexual dysfunction, cognitive impairment, and fatigue. Newer antidepressants are explored with the goal of more optimally treating these non-mood-related symptoms of MDD. The 3 oral antidepressants that have been FDA-approved most recently include vortioxetine, vilazodone, and levomilnacipran. Unique features of these antidepressants are explored through 3 patient cases.
虽然重度抑郁症(MDD)部分特征表现为情绪变化,但其他症状也会造成严重损害,包括性功能障碍、认知障碍和疲劳。人们正在探索新型抗抑郁药,以期更有效地治疗MDD这些与情绪无关的症状。美国食品药品监督管理局(FDA)最近批准的3种口服抗抑郁药包括伏硫西汀、维拉唑酮和左旋米那普明。通过3个患者案例探讨了这些抗抑郁药的独特特性。