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小儿麻醉中使用与不使用肌肉松弛剂插入喉罩气道的比较:一项随机临床试验。

Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial.

作者信息

Totonchi Ziae, Seyed Siamdoust Seyed Alireza, Zaman Behrooz, Rokhtabnak Faranak, Alavi Seyyed Amin

机构信息

Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Pain Research Center, Department of Anesthesiology and Pain Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Heliyon. 2022 Nov 13;8(11):e11504. doi: 10.1016/j.heliyon.2022.e11504. eCollection 2022 Nov.

Abstract

INTRODUCTION

This study aimed to evaluate the effectiveness of using muscle relaxant on the ease of laryngeal mask airway (LMA) insertion and possibility of its related complications.

METHODS

This double-blind, randomized clinical trial was performed on 60 children aged 1-4 years with ASA (American Society of Anesthesiology) I or II with upper limb injuries who were candidates for surgery. The patients were randomly allocated to the two groups receiving atracurium group as muscle relaxant (MR) or saline group (S).

RESULTS

Regarding ease of placement, the LMA was inserted in 66.7% and 63.3% of patients straightforwardly in the MR and S groups, respectively. While it was performed with one maneuver in 23.3% and 26.7% of cases in the MR and S groups, respectively (p = 0.955). Moreover, LMA dislodgment in the two groups was 36.7% in the MR group and 20.0% in the S group without a meaningful difference (P = 0.152). The only complication observed in the two groups was laryngospasm, which occurred in 0.10% and 13.3% in the MR and S groups, respectively (p = 0.688).

CONCLUSION

In some pediatric anesthesia, the use of atracurium, as a muscle relaxant had no significant effect on capability of LMA insertion, maintaining airway patency, LMA seal pressure and oxygenation variations. Moreover, it did not have a preventive effect on the occurrence of complications such as laryngospasm.

摘要

引言

本研究旨在评估使用肌肉松弛剂对喉罩气道(LMA)插入的难易程度及其相关并发症发生可能性的影响。

方法

本双盲、随机临床试验对60例年龄在1至4岁、ASA(美国麻醉医师协会)分级为I或II级、上肢受伤且拟行手术的儿童进行。患者被随机分为两组,分别接受阿曲库铵作为肌肉松弛剂(MR)组或生理盐水组(S)。

结果

关于放置的难易程度,LMA在MR组和S组中分别直接插入了66.7%和63.3%的患者。而在MR组和S组中,分别有23.3%和26.7%的病例通过一次操作完成(p = 0.955)。此外,两组中LMA移位情况在MR组为36.7%,在S组为20.0%,无显著差异(P = 0.152)。两组中观察到的唯一并发症是喉痉挛,在MR组和S组中分别发生率为0.10%和13.3%(p = 0.688)。

结论

在某些小儿麻醉中,使用阿曲库铵作为肌肉松弛剂对LMA插入能力、维持气道通畅、LMA密封压力及氧合变化无显著影响。此外,它对喉痉挛等并发症的发生没有预防作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/641a/9672355/dd97031b7788/gr1.jpg

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