Department of Ophthalmology, Inha University School of Medicine, Incheon, Republic of Korea.
Ocul Immunol Inflamm. 2024 Jan;32(1):31-39. doi: 10.1080/09273948.2022.2148112. Epub 2022 Nov 28.
Frosted branch angiitis (FBA) is a rare form of retinal vasculitis. Four case series and an extensive literature review of 236 cases were conducted to clarify the characteristics of this rare condition.
Case series and literature review.
An analysis of the reported cases revealed that a majority (54.6%) developed FBA in the presence of an underlying disease, with recurrence and complications requiring surgical intervention being rare. The frequency of bilateral occurrence (55.0%) and prevalence in female patients (45.0%) were noted to be lower than previously reported.
In general, idiopathic FBAs are more likely to be bilateral and diagnosed at a younger age than secondary FBAs. In idiopathic FBA, fundus involvement is more generalized, exudates tend to be more translucent, and extensive retinal hemorrhage tends to be less frequent. However, there were no differential characteristic fundus features that clearly distinguished idiopathic FBA from secondary FBA.
白塞氏树枝状血管炎(FBA)是一种罕见的视网膜血管炎。通过对 4 个病例系列和对 236 例的广泛文献回顾,阐明了这种罕见疾病的特征。
病例系列和文献回顾。
对报道的病例进行分析表明,大多数(54.6%)患者在存在基础疾病的情况下发生 FBA,复发和需要手术干预的并发症较为罕见。双侧发生的频率(55.0%)和女性患者的患病率(45.0%)低于之前的报道。
一般来说,特发性 FBA 比继发性 FBA 更可能是双侧的,且发病年龄更小。在特发性 FBA 中,眼底受累更为广泛,渗出物往往更透明,广泛的视网膜出血也不太常见。然而,并没有明显区分特发性 FBA 和继发性 FBA 的特征性眼底特征。