Department of Ophthalmology, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Department of Ophthalmology, University College Hospital Ibadan, Ibadan, Nigeria.
PLoS One. 2022 Dec 1;17(12):e0278286. doi: 10.1371/journal.pone.0278286. eCollection 2022.
Genomics, an emerging field to improve public health practice, has potential benefits to understanding ocular diseases. This study explored the social construction of genomics in ocular diseases in the blind community in Ibadan, Nigeria, through two focus group discussions and twelve in-depth interview sessions conducted among people living with ocular disorders. The data were thematic and content-analysed. Although the participants had limited knowledge about ocular diseases, genomics, and their nexus, they maintained a positive attitude toward its potential benefits. This informed their willingness to participate in genomics testing for ocular diseases. The participants preferred saliva-based sample collection over blood-based, and expressed concern for the procedure and accrued benefits of genomics studies. Thus, public sensitisation about ocular diseases and client-centred genomics testing procedures should be engendered.
基因组学是一个新兴的领域，可以改善公共卫生实践，对于理解眼部疾病具有潜在的好处。本研究通过在尼日利亚伊巴丹的盲人社区进行的两次焦点小组讨论和十二次深入访谈，探讨了基因组学在眼部疾病中的社会构建。数据进行了主题和内容分析。尽管参与者对眼部疾病、基因组学及其联系的了解有限，但他们对其潜在好处持积极态度。这使他们愿意参与眼部疾病的基因组学检测。参与者更喜欢基于唾液的样本采集而不是基于血液的样本采集，并对基因组学研究的程序和获得的益处表示关注。因此，应该进行眼部疾病的公众宣传和以客户为中心的基因组学检测程序。
