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中药补品治疗 COVID-19 德尔塔变异株引起的嗅觉障碍的安全性和有效性:系统评价和荟萃分析方案。

Safety and efficacy of Chinese herbal tonics for the treatment of olfactory disorders caused by the Delta strain in COVID-19: A protocol for systematic review and meta-analysis.

机构信息

College of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.

出版信息

Medicine (Baltimore). 2022 Dec 2;101(48):e31827. doi: 10.1097/MD.0000000000031827.


DOI:10.1097/MD.0000000000031827
PMID:36482602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9726399/
Abstract

BACKGROUND: Coronavirus disease 2019 (COVID-19) is an acute respiratory infectious disease that makes breathing difficult and is often accompanied by olfactory disorders and distension. Chinese herbal tonics, a special external treatment of traditional Chinese medicine, has shown beneficial effects in the treatment of olfactory disorders. Currently, there is a lack of systematic reviews on Chinese herbal tonics for the treatment of olfactory disorders. We conduct this study to evaluate the efficacy and safety of Chinese herbal tonics in the treatment of olfactory disorders. This study is designed to evaluate the effectiveness and safety of Chinese herbal tonics for olfactory disorders in COVID-19. METHODS: Randomized controlled trials from December 2019 to September 2022. will be included, without restrictions on language or publication date. PubMed, EMBASE, Cochrane Library, Web of Science, Chinese Biomedical Databases, China National Knowledge Infrastructure, Wanfang Database, and VIP Database were searched. Two researchers will independently select studies, extract data, and evaluate study quality. The Cochrane risk of bias tool for randomized trials will be used to assess the risk of bias in the included studies. Statistical analyses will be conducted using the Review Manager (RevMan 5.3, Cochrane Collaboration, Nordic Cochrane Center, Copenhagen, Denmark). RESULTS: This study aimed to prove the efficacy and safety of Chinese herbal tonics for olfactory disorders in patients with COVID-19. Our study provides a more accurate treatment method for olfactory disorders during COVID-19.We will publish our results in a peer-reviewed journal.

摘要

背景:2019 年冠状病毒病(COVID-19)是一种急性呼吸道传染病,导致呼吸困难,常伴有嗅觉障碍和膨胀。中草药滋补品是一种特殊的中医外治法,在治疗嗅觉障碍方面显示出有益的效果。目前,关于中草药滋补品治疗嗅觉障碍的系统评价还比较缺乏。我们进行这项研究是为了评估中草药滋补品治疗嗅觉障碍的疗效和安全性。本研究旨在评估中草药滋补品治疗 COVID-19 嗅觉障碍的有效性和安全性。

方法:我们将纳入 2019 年 12 月至 2022 年 9 月的随机对照试验,不限制语言或发表日期。我们将检索 PubMed、EMBASE、Cochrane 图书馆、Web of Science、中国生物医学文献数据库、中国知网、万方数据库和维普数据库。两名研究人员将独立选择研究、提取数据并评估研究质量。我们将使用 Cochrane 偏倚风险工具评估纳入研究的偏倚风险。统计分析将使用 Review Manager(RevMan 5.3,Cochrane 协作组,北欧 Cochrane 中心,哥本哈根,丹麦)进行。

结果:本研究旨在证明中草药滋补品治疗 COVID-19 患者嗅觉障碍的疗效和安全性。我们的研究为 COVID-19 期间的嗅觉障碍提供了一种更准确的治疗方法。我们将在同行评议的期刊上发表我们的研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec62/9726399/9ea2b9a91276/medi-101-e31827-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec62/9726399/9ea2b9a91276/medi-101-e31827-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec62/9726399/9ea2b9a91276/medi-101-e31827-g001.jpg

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引用本文的文献

[1]
Exploring the research landscape of COVID-19-induced olfactory dysfunction: A bibliometric study.

Front Neurosci. 2023-3-24

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