Anant Bajaj Retina Institute, L V Prasad Eye Institute (LVPEI), Hyderabad, India.
Jhaveri Microbiology Centre, LVPEI, Hyderabad, India.
Am J Trop Med Hyg. 2022 Dec 12;108(1):27-30. doi: 10.4269/ajtmh.22-0441. Print 2023 Jan 11.
Pythium insidiosum is a parasitic oomycete that can cause keratitis and closely resembles fungus, both clinically and morphologically. It requires a trained microbiologist for its differentiation from fungal filaments and has poor response to antifungal therapy. We present a case of primary isolation of the organism from the vitreous cavity in a case of endophthalmitis. The infection spread quickly and involved all the ocular tissues. The eye had poor visual outcome despite a sequence of rapidly completed retinal and corneal surgeries along with initiation of anti-Pythium therapy.
棘蛙属是一种寄生的卵菌,可引起角膜炎,在临床上和形态上与真菌非常相似。它需要经过专门的微生物学家进行区分,与真菌丝不同,而且对抗真菌治疗反应不佳。我们报告了一例眼内炎病例中从玻璃体腔中首次分离出该病原体。感染迅速扩散,累及所有眼组织。尽管迅速完成了一系列视网膜和角膜手术,并开始了抗棘蛙属治疗,但眼睛的视力预后仍然很差。