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垂体卒中(PA):一例已知垂体腺瘤患者罕见临床综合征的延迟诊断

Pituitary Apoplexy (PA): Delayed Diagnosis of a Rare Clinical Syndrome in a Patient With a Known Pituitary Adenoma.

作者信息

Mehkri Yusuf, Leone Emma, Sharaf Ramy, Hernandez Jairo, Figueredo Rivas Lorena, Tuna Ibrahim S, Shuhaiber Hans

机构信息

College of Medicine, University of Florida College of Medicine, Gainesville, USA.

Neurology, University of Florida College of Medicine, Gainesville, USA.

出版信息

Cureus. 2022 Nov 15;14(11):e31536. doi: 10.7759/cureus.31536. eCollection 2022 Nov.

Abstract

Pituitary apoplexy (PA) is a rare clinical syndrome in which the pituitary gland undergoes infarction or hemorrhage, predominantly in the setting of an underlying tumor. We report on apoplexy of an expanding pituitary macroadenoma that was compressing the optic chiasm in a patient with progressively worsening neurologic deficits. Due to the patient's rapidly declining clinical status and family's goals of care, no neurosurgical intervention took place, and the patient expired a few days following discharge to hospice. This case highlights the importance of early suspicion for apoplexy in a patient with a history of pituitary adenoma and signs of neurologic deficit.

摘要

垂体卒中(PA)是一种罕见的临床综合征,其中垂体发生梗死或出血,主要发生在存在潜在肿瘤的情况下。我们报告了一例正在增大的垂体大腺瘤卒中病例,该腺瘤压迫视交叉,导致一名患者的神经功能缺损逐渐恶化。由于患者临床状况迅速恶化且家属的护理目标,未进行神经外科干预,患者在转至临终关怀机构几天后死亡。该病例强调了对于有垂体腺瘤病史且出现神经功能缺损体征的患者早期怀疑垂体卒中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c018/9754063/9fe13cf7d735/cureus-0014-00000031536-i01.jpg

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