Department of Pathology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Med Sci Monit Basic Res. 2022 Dec 8;28:e938176. doi: 10.12659/MSMBR.938176.
BACKGROUND Kidney disease is hard to detect at its early stage; therefore, the Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guideline was developed for improving care and outcomes of patients with kidney disease. This study aimed to determine clinical outcomes from applying this guideline in a community hospital service. MATERIAL AND METHODS The patients' data were extracted from their medical records and analyzed for outcomes of using the estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) for detecting kidney disease. RESULTS The eGFR was utilized in 36 172 patients aged ≥18 years, and 76.86% of them had normal kidney function. The prevalence of chronic kidney disease (CKD) was 8.20%; most patients (68%) with CKD were in stages 3a and 3b. The most common causes of CKD were diabetes and hypertension. The UACR was mainly used in patients with diabetes. The percentage of patients with UACR ≥3 mg/mmol creatinine alone was significantly higher than that of patients with eGFR.
肾脏疾病在早期难以检测;因此,改善全球肾脏病预后组织(KDIGO)2012 指南旨在改善肾脏病患者的护理和预后。本研究旨在确定在社区医院服务中应用该指南的临床结果。
从患者的病历中提取数据,分析使用估算肾小球滤过率(eGFR)和尿白蛋白-肌酐比值(UACR)检测肾脏疾病的结果。
该研究共纳入了 36172 名年龄≥18 岁的患者,其中 76.86%的患者肾功能正常。慢性肾脏病(CKD)的患病率为 8.20%;CKD 患者中大多数(68%)处于 3a 和 3b 期。导致 CKD 的最常见原因是糖尿病和高血压。UACR 主要用于患有糖尿病的患者。单独使用 UACR≥3mg/mmol 肌酐的患者比例明显高于 eGFR。