肘关节周围软组织肉瘤的临床结果：一项单机构回顾性研究
Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study.
作者信息
Azurin Edelyn S, Yamamoto Norio, Hayashi Katsuhiro, Takeuchi Akihiko, Tada Kaoru, Miwa Shinji, Igarashi Kentaro, Higuchi Takashi, Yonezawa Hirotaka, Morinaga Sei, Asano Yohei, Saito Shiro, Tsuchiya Hiroyuki
机构信息
Department of Orthopedic Surgery, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Department of Orthopedics, Jose B. Lingad Memorial General Hospital, San Fernando, Pampanga, Philippines.
出版信息
Sarcoma. 2022 Dec 17;2022:1087726. doi: 10.1155/2022/1087726. eCollection 2022.
BACKGROUND
We report a retrospective case series analysis of clinical outcomes of patients with soft tissue sarcoma around the elbow.
METHODS
Twenty-two patients underwent surgical tumor excision between January 1999 and May 2017, with a mean follow-up of 85.2 months.
RESULTS
Six tumors were localized in the upper arm, nine in the elbow, and seven in the forearm. Sixteen tumors were deep-seated, and six were superficially located. Fifteen patients underwent wide excision, including one amputation, and 18 achieved (81.8%) negative margins histologically. Two local recurrences and four distant metastases developed. The mean Musculoskeletal Tumor Society score was 92.0% (range, 33.3-100). The 5-year local recurrence-free survival rate, metastasis-free survival rate, and overall survival rate were 90.0%, 77.0%, and 79.7%, respectively.
CONCLUSIONS
Local control and limb function can have favorable outcomes when the tumor excised has a histologically negative margin without sacrificing the major structure.
背景
我们报告了一项关于肘部周围软组织肉瘤患者临床结局的回顾性病例系列分析。
方法
1999年1月至2017年5月期间，22例患者接受了肿瘤手术切除，平均随访85.2个月。
结果
6个肿瘤位于上臂，9个位于肘部，7个位于前臂。16个肿瘤为深部肿瘤，6个为浅表肿瘤。15例患者接受了广泛切除，包括1例截肢，18例（81.8%）组织学切缘阴性。出现2例局部复发和4例远处转移。肌肉骨骼肿瘤学会平均评分为92.0%（范围为33.3 - 100）。5年无局部复发生存率、无转移生存率和总生存率分别为90.0%、77.0%和79.7%。
结论
当切除的肿瘤组织学切缘阴性且不牺牲主要结构时，局部控制和肢体功能可取得良好结局。
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