Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ordu University, Ordu, Turkey.
Department of Medical Microbiology, Faculty of Medicine, Ordu University, BucakMah. NefsiBucak Cad. 52200, Ordu, Turkey.
J Med Case Rep. 2022 Dec 30;16(1):492. doi: 10.1186/s13256-022-03702-2.
Brucellosis is one of the most common zoonotic diseases in the world. Osteoarticular complications, especially vertebral system involvement, are most commonly reported. However, reports and coreports of pulmonary complications and thoracal spondylodiscitis and epidural abscess are rare.
Spondylodiscitis was detected at the T11-12 vertebral level, followed by epidural and paravertebral abscess, and then empyema was detected in a 17-year-old Asian female patient without any additional disease. The patient had used various antibiotics and the disease could not be proven bacteriologically. Also, the Rose Bengal test was negative. However, serologically high titer Brucella positivity was detected in the blood and pleural fluid sample. Drainage was required for bilateral empyema. Disease duration prolonged due to multiple complications. The patient was cured with combined long-term treatment for brucellosis.
Although some are rare, brucellosis is a zoonotic disease that can cause many complications. The gold standard for diagnosis is the growth of bacteria in blood culture or tissue culture. However, isolation of the microorganism can be very difficult. Clinical suspicion and serological tests are important guides.
布鲁氏菌病是世界上最常见的人畜共患疾病之一。最常报告的是骨关节炎并发症,尤其是脊椎系统受累。然而,肺部并发症以及胸椎间盘炎和硬膜外脓肿的报告和核心报告较为罕见。
一名 17 岁的亚洲女性患者无其他疾病,在 T11-12 椎体水平检测到椎间盘炎,随后出现硬膜外和椎旁脓肿,然后在胸腔中检测到积脓。该患者已使用各种抗生素,但无法从细菌学上证实该疾病。此外,红斑试验呈阴性。然而,在血液和胸腔积液样本中检测到血清学高滴度布鲁氏菌阳性。双侧积脓需要引流。由于多种并发症,疾病持续时间延长。该患者通过联合长期布鲁氏菌病治疗而痊愈。
尽管有些情况较为罕见,但布鲁氏菌病是一种人畜共患疾病,可引起许多并发症。诊断的金标准是血液或组织培养中细菌的生长。然而,微生物的分离可能非常困难。临床怀疑和血清学检测是重要的指导。