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慢性持续性腹膜透析患者的女性和男性性功能障碍。

Sexual dysfunction in female and male patients undergoing chronic ambulatory peritoneal dialysis.

机构信息

Department of Internal Medicine, Division of Nephrology, Konya Beyhekim Training and Research Hospital, Konya, Turkey.

Department of Internal Medicine, Division of Nephrology, Meram School of Medicine, Konya, Turkey.

出版信息

Int J Artif Organs. 2023 Feb;46(2):74-80. doi: 10.1177/03913988221145505. Epub 2022 Dec 30.

Abstract

BACKGROUND

To prolong survival and to provide a better quality of life (QoL) are two aims at the forefront in the care of peritoneal dialysis (PD) patients. In this study we aimed to determine frequency of sexual dysfunction (SD) and influencing factors in PD patients.

METHODS

Of the 201 patients, 114 under 65 years and on chronic ambulatory PD for at least 3 months were enrolled. Forty-nine females and 65 males completed the study. Survey forms were applied using face-to-face interview method. Female Sexual Function Index (FSFI) was used to assess SD in women; International Index for Erectile Function (IIEF) was used to assess erectile dysfunction (ED) in men. All patients completed SF-36 and Beck Depression Inventory (BDI) forms.

RESULTS

While SD was evident in 89.8% of female patients (FSFI score:10.4 ± 9.7), ED was present in 87.7% of males (IIEF score:13.8 ± 7.9). Depression rates were 65.3% and 49.2% in female and male patients, respectively. BDI scores were 21.6 ± 10.4 and 17.1 ± 9.5; physical component scores, 52.6 ± 20.4 and 55.2 ± 20.2; mental component scores, 45.2 ± 19.8 and 49.9 ± 22, in female and male patients, respectively. FSFI was correlated with age (β = -0.53  < 0.001) and BDI score (β = -0.23  = 0.04), ( = 0.64). ED showed correlation with age (β = -0.36  < 0.001), BDI score (β = -0.57  < 0.001), and hemoglobin level (β = 0.26  = 0.003), ( = 0.74).

CONCLUSION

SD, often overlooked and not discussed by both patients and physicians, is encountered relatively frequently among PD patients. Left not discussed and untreated SD may adversely affect QoL.

摘要

背景

延长生存时间和提高生活质量(QoL)是腹膜透析(PD)患者护理的两个主要目标。本研究旨在确定 PD 患者性功能障碍(SD)的发生频率及其影响因素。

方法

纳入了 201 例患者,其中 114 例年龄小于 65 岁且接受慢性间歇性 PD 至少 3 个月。49 名女性和 65 名男性完成了研究。采用面对面访谈方法应用问卷调查表。女性采用女性性功能指数(FSFI)评估 SD;男性采用国际勃起功能指数(IIEF)评估勃起功能障碍(ED)。所有患者均完成 SF-36 和贝克抑郁量表(BDI)。

结果

89.8%的女性患者(FSFI 评分:10.4±9.7)存在 SD,87.7%的男性患者(IIEF 评分:13.8±7.9)存在 ED。女性和男性患者的抑郁发生率分别为 65.3%和 49.2%。BDI 评分分别为 21.6±10.4 和 17.1±9.5;生理成分评分分别为 52.6±20.4 和 55.2±20.2;心理成分评分分别为 45.2±19.8 和 49.9±22。FSFI 与年龄呈负相关(β=-0.53,P<0.001)和 BDI 评分(β=-0.23,P=0.04),(r=0.64)。ED 与年龄呈负相关(β=-0.36,P<0.001),BDI 评分(β=-0.57,P<0.001)和血红蛋白水平(β=0.26,P=0.003),(r=0.74)。

结论

SD 是 PD 患者中相对常见的问题,但常被患者和医生忽视和未予讨论。如果不讨论和不治疗 SD,可能会对 QoL 产生不利影响。

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