Ghose Sarah M, Riedy Dana, Dautovich Natalie D
Department of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.
Behavioral Health Interdisciplinary Program, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA.
Women Health. 2023 Feb;63(2):115-124. doi: 10.1080/03630242.2022.2161695. Epub 2023 Jan 1.
Poor sleep is a reality for many midlife women experiencing menopause. Although much empirical attention has been allocated toward ameliorating vasomotor symptoms and related consequences, less focus has been given toward sleep, specifically sleep variability, in menopausal women. The present study aimed to determine the association between menopausal symptoms and night-to-night sleep variability among peri- and post-menopausal women. Participants were 220 menopausal women (42.3 percent peri-menopausal, 57.7 percent post-menopausal) aged 40 to 64 from the United States recruited via Prolific, and online platform. The current study conducted secondary analyses on data collected as part of a larger investigation on midlife women from the United States. A structural equation model assessed associations between a latent menopausal symptom construct, composed of several Women's Health Questionnaire domains, and a latent sleep variability construct, composed of sleep diary indices. Menopausal symptoms were associated with latent sleep variability ( = 0.49, < .05); greater experience of menopausal symptoms was associated with more night-to-night sleep variability (medium effect size). Waking after sleep onset (WASO) was the sole significant indicator of the latent sleep factor. The findings highlight the importance of menopausal symptoms for sleep variability, specifically wakefulness. As such, wakefulness may be an important target for sleep interventions for menopausal women. The findings further suggest a need for more research and interventions targeted toward understanding and ameliorating the impact of menopausal symptoms on night-to-night wakefulness overall.
睡眠质量差是许多处于更年期的中年女性面临的现实情况。尽管已经投入了大量实证研究来改善血管舒缩症状及相关后果，但对于更年期女性的睡眠，尤其是睡眠变异性的关注较少。本研究旨在确定围绝经期和绝经后女性的更年期症状与夜间睡眠变异性之间的关联。研究参与者为220名年龄在40至64岁之间的更年期女性（42.3%为围绝经期，57.7%为绝经后），她们通过在线平台Prolific从美国招募而来。本研究对作为美国中年女性一项更大规模调查的一部分所收集的数据进行了二次分析。一个结构方程模型评估了由几个妇女健康问卷领域组成的潜在更年期症状结构与由睡眠日记指数组成的潜在睡眠变异性结构之间的关联。更年期症状与潜在睡眠变异性相关（r = 0.49，p <.05）；更年期症状体验越强烈，夜间睡眠变异性越大（效应量中等）。入睡后觉醒（WASO）是潜在睡眠因子的唯一显著指标。研究结果凸显了更年期症状对睡眠变异性，尤其是清醒状态的重要性。因此，清醒状态可能是更年期女性睡眠干预的一个重要目标。研究结果进一步表明，需要开展更多研究和干预措施，以理解和改善更年期症状对夜间整体清醒状态的影响。
