Department of General Surgery, University of Health Sciences, İstanbul Prof. Dr. Cemil Taşçıoğlu City Hospital, İstanbul-Türkiye.
Ulus Travma Acil Cerrahi Derg. 2022 Dec;29(1):109-115. doi: 10.14744/tjtes.2022.42738.
The objective of the study was to investigate risk factors affecting mortality rates in patients with Fournier's gangrene (FG) and develop methods to increase the survival rate.
We collected data of 73 patients treated for FG between February 2012 and June 2021 at Istanbul Professor Doctor Cemil Taşçıoğlu City Hospital General Surgery Clinic. The data of living patients (Group 1, n=56) and deceased patients (Group 2, n=17) were analyzed separately. Demographic data of patients were sex, age, infection rate, Uludag FG severity index (UFGSI) scores and FG severity index (FGSI) scores, urea serum levels, the source of infection, the presence of diabetes, obesity, the presence of diversion stoma, duration of vacuum-assisted closure treatment in days, hospitalization time in days, intensive care period in days, and isolated bacterial species.
The mortality rate was 23%. A significant difference in age and dissemination score of the infection was found between the two groups. According to UFGSI and FGSI scores, the scores of the two groups of patients were significantly higher. The UFGSI had 100% sensitivity and 68% sensitivity. FGSI had 82% sensitivity and 58% specificity. The cutoff values for UFGSI and FGSI were 8 and 6, respectively.
Age and dissemination scores of diseases were important factors that cause mortality in patients with FG. However, an accurate scoring system is important in predicting patients to be treated in the intensive care unit (ICU). Patients with a UFGSI score above 8 face a higher risk of death and should be treated in the ICU.
本研究的目的是探讨影响 Fournier 坏疽(FG)患者死亡率的危险因素,并寻找提高生存率的方法。
我们收集了 2012 年 2 月至 2021 年 6 月在伊斯坦布尔教授博士 Cemil Taşçıoğlu 城市医院普外科诊所治疗的 73 例 FG 患者的数据。分别分析了存活患者(第 1 组,n=56)和死亡患者(第 2 组,n=17)的数据。患者的人口统计学数据包括性别、年龄、感染率、乌尔达格 FG 严重指数(UFGSI)评分和 FG 严重指数(FGSI)评分、血清尿素水平、感染源、糖尿病、肥胖、转流造口存在情况、负压封闭治疗天数、住院天数、重症监护天数和分离的细菌种类。
死亡率为 23%。两组间年龄和感染扩散评分差异有统计学意义。根据 UFGSI 和 FGSI 评分,两组患者的评分均显著升高。UFGSI 的敏感性为 100%,特异性为 68%。FGSI 的敏感性为 82%,特异性为 58%。UFGSI 和 FGSI 的截断值分别为 8 和 6。
年龄和疾病的扩散评分是 FG 患者死亡的重要因素。然而,准确的评分系统对预测需要在重症监护病房(ICU)治疗的患者非常重要。UFGSI 评分高于 8 的患者死亡风险更高,应在 ICU 治疗。