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Divergent and dominant anti-inflammatory effects of patient-derived anticitrullinated protein antibodies (ACPA) in arthritis development.

作者信息

Raposo Bruno, Afonso Marcelo, Israelsson Lena, Wähämaa Heidi, Stålesen Ragnhild, Wermeling Fredrik, Hensvold Aase Haj, Grönwall Caroline, Rethi Bence, Klareskog Lars, Malmström Vivianne

机构信息

Department of Medicine, Karolinska Universitetssjukhuset i Solna, Stockholm, Sweden

Department of Medicine, Karolinska Universitetssjukhuset i Solna, Stockholm, Sweden.

出版信息

Ann Rheum Dis. 2023 May;82(5):724-726. doi: 10.1136/ard-2022-223417. Epub 2023 Jan 5.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3897/10176372/c74ea4b5c603/ard-2022-223417f01.jpg

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Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications.
Ann Rheum Dis. 2020 Apr;79(4):472-480. doi: 10.1136/annrheumdis-2019-216499. Epub 2020 Feb 10.
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Pathogenic Citrulline-Multispecific B Cell Receptor Clades in Rheumatoid Arthritis.
Arthritis Rheumatol. 2018 Dec;70(12):1933-1945. doi: 10.1002/art.40590. Epub 2018 Oct 18.

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