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鼻腔莫匹罗星治疗对入住新生儿重症监护病房的儿童患者耐甲氧西林金黄色葡萄球菌鼻腔外携带的影响。

Effect of nasal mupirocin treatment on extranasal carriage of methicillin-resistant among pediatric patients admitted to the neonatal intensive care unit.

机构信息

Department of Neonatology, Takatsuki General Hospital, Takatsuki, Osaka, Japan.

出版信息

Infect Control Hosp Epidemiol. 2023 Jul;44(7):1174-1176. doi: 10.1017/ice.2022.311. Epub 2023 Jan 11.

Abstract

Decolonization of MRSA detected in the oral cavity and tracheal aspirates occurred in 85% and 58% of neonates, respectively, with nasal mupirocin treatment. Recurrent MRSA colonization occurred in 45% of neonates whose MRSA was detected in the oral cavity at a mean of 19 days. Recurrent MRSA colonization occurred in 58% of neonates whose MRSA was detected in tracheal aspirates at a mean of 23 days.

摘要

经鼻腔涂抹莫匹罗星后,分别有 85%和 58%的新生儿口腔和气管抽吸物中的耐甲氧西林金黄色葡萄球菌(MRSA)被清除。在平均 19 天口腔 MRSA 检测阳性的新生儿中,有 45%出现 MRSA 复发性定植。在平均 23 天气管抽吸物 MRSA 检测阳性的新生儿中,有 58%出现 MRSA 复发性定植。

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