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膀胱尿路上皮癌伴鳞状细胞分化的孤立性心脏转移——一种罕见表现。

Solitary cardiac metastasis of urothelial carcinoma of the urinary bladder with squamous cell differentiation - a rare manifestation.

作者信息

Duwe Gregor, Fischer Nikita Dhruva, Haack Maximilian, Höfner Thomas, Haferkamp Axel, Brandt Maximilian Peter

机构信息

Department of Urology and Pediatric Urology, Johannes-Gutenberg University Medical Center, Mainz, Germany.

出版信息

Urol Case Rep. 2023 Jan 2;46:102318. doi: 10.1016/j.eucr.2023.102318. eCollection 2023 Jan.

Abstract

We present a case of bladder cancer with a singular cardiac metastasis. A 51-year-old female patient was referred to our department for painless macrohematuria. We confirmed the diagnosis of muscle-invasive urothelial carcinoma of the urinary bladder with partial squamous cell differentiation. Computed tomography (CT) staging demonstrated a singular cardiac metastasis. Two months after receiving six cycles of chemotherapy control CT scan revealed massive tumour progression. The singular cardiac metastasis size increased to approximately two thirds of right ventricle size. Singular cardiac metastases of urothelial carcinoma are extremely rare and show rapid progression, hence introduction to therapy should not be delayed.

摘要

我们报告一例膀胱癌伴孤立性心脏转移的病例。一名51岁女性患者因无痛性肉眼血尿转诊至我科。我们确诊为膀胱肌层浸润性尿路上皮癌伴部分鳞状细胞分化。计算机断层扫描(CT)分期显示有孤立性心脏转移。接受六个周期化疗控制后两个月,CT扫描显示肿瘤大量进展。孤立性心脏转移灶大小增加至约右心室大小的三分之二。尿路上皮癌的孤立性心脏转移极为罕见且进展迅速,因此不应延迟治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21ef/9827352/e3d5524e79ec/gr1.jpg

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