Department of Urology and Urological Oncology, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.
Int J Environ Res Public Health. 2023 Jan 4;20(2):944. doi: 10.3390/ijerph20020944.
Prostate cancer is being detected in increasingly younger men. These patients expect to preserve their current quality of life and quickly recover after treatment. Medical technology and surgical techniques are advancing along with the growing expectations of patients. In addition, the universal method of assessing the quality of outcomes after operations is constantly being researched. As of today, biochemical remission alone, after radical prostatectomy, is insufficient for the patient. Therefore, multi-parametric evaluation methods are being developed, such as trifecta, which assesses biochemical remission, continence, and erectile function. The improvement over the trifecta is the pentafecta, which additionally evaluates postoperative complications and infiltration of surgical margins. Our study was conducted within a group of patients who were surgically treated for prostate cancer in 2017 at the Clinic of Urology and Urological Oncology of the Pomeranian Medical University. We recruited 237 men for the study. From that group, 131 men met the criteria to be included in the analysis. Maintaining continence (87.78%) is the easiest pentafecta parameter to obtain and will have the greatest impact on quality of life in the future. Maintaining biochemical remission (82.44%) is the second most important aspect for the patient. Retaining erectile function is the most difficult pentafecta parameter to obtain (29.01%) while having little impact on the quality of life. Negative surgical margins (66.41%) showed a negligible impact on the quality of life. The occurrence of complications (32.07%) has a negative impact on the quality of life of patients, but only during the treatment of complications.
前列腺癌在越来越年轻的男性中被检测到。这些患者期望保持当前的生活质量,并在治疗后迅速康复。医疗技术和手术技术随着患者期望的增长而不断进步。此外,不断研究评估手术后结果质量的通用方法。截至今天,根治性前列腺切除术后仅生化缓解对患者来说是不够的。因此,正在开发多参数评估方法,如 trifecta,它评估生化缓解、控尿和勃起功能。比 trifecta 更先进的是 pentafecta,它还评估术后并发症和手术切缘浸润。我们的研究是在 2017 年在波美拉尼亚医科大学泌尿科和泌尿科肿瘤学诊所接受前列腺癌手术治疗的一组患者中进行的。我们招募了 237 名男性进行研究。在该组中,有 131 名男性符合纳入分析的标准。保持控尿(87.78%)是获得 pentafecta 最容易的参数,并且将对未来的生活质量产生最大影响。保持生化缓解(82.44%)是患者的第二重要方面。保留勃起功能是获得最困难的 pentafecta 参数(29.01%),同时对生活质量的影响很小。阴性手术切缘(66.41%)对生活质量的影响可以忽略不计。并发症的发生(32.07%)对患者的生活质量有负面影响,但仅在治疗并发症期间。