[一例原发性膀胱黏膜相关淋巴组织（MALT）淋巴瘤]

[A CASE OF PRIMARY MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) LYMPHOMA OF THE URINARY BLADDER].

作者信息

Imamura Tetsuya, Miyachi Shiori, Horiuchi Eiho, Ikeda Takeshi

机构信息

The Department of Urology, Ise Municipal General Hospital.

The Department of Internal Medicine, Ise Municipal General Hospital.

出版信息

Nihon Hinyokika Gakkai Zasshi. 2022;113(1):28-32. doi: 10.5980/jpnjurol.113.28.

DOI:10.5980/jpnjurol.113.28

PMID:36682809

Abstract

A 68-year-old female presented with macroscopic hematuria. Cystoscopy revealed a wide-based submucosal mass. Computed tomography revealed a 3.5 × 2.5-cm solitary mass situated from the trigone to the left lateral bladder wall and the left hydroureter and hydronephrosis. T2-weighted magnetic resonance imaging (MRI) revealed low intensity, and diffusion-weighed MRI showed increased diffusion without invasion. The bladder tumor was immediately resected transurethrally. Histological diagnosis of the tissue obtained by transurethral resection was extranodal marginal zone B cell lymphoma of MALT. Positron emission tomography-CT showed no lesions other than the bladder tumor. The patient was diagnosed with stage-IE lymphoma of the bladder (Ann Arbor classification). Radiotherapy was performed at the bladder and pelvis (30 Gy) with six courses of rituximab (375 mg/m). No local or distant recurrence after a 48-month follow-up was noted.

摘要

一名68岁女性出现肉眼血尿。膀胱镜检查发现一个基底较宽的黏膜下肿块。计算机断层扫描显示一个3.5×2.5厘米的孤立肿块，位于膀胱三角区至左侧膀胱壁，伴有左侧输尿管积水和肾盂积水。T2加权磁共振成像（MRI）显示低信号强度，扩散加权MRI显示扩散增加但无浸润。膀胱肿瘤立即经尿道切除。经尿道切除组织的组织学诊断为黏膜相关淋巴组织边缘区B细胞淋巴瘤。正电子发射断层扫描-CT显示除膀胱肿瘤外无其他病变。该患者被诊断为膀胱IE期淋巴瘤（Ann Arbor分期）。对膀胱和骨盆进行了放疗（30 Gy），并给予六个疗程的利妥昔单抗（375 mg/m²）治疗。48个月随访后未发现局部或远处复发。