Imamura Tetsuya, Miyachi Shiori, Horiuchi Eiho, Ikeda Takeshi
The Department of Urology, Ise Municipal General Hospital.
The Department of Internal Medicine, Ise Municipal General Hospital.
Nihon Hinyokika Gakkai Zasshi. 2022;113(1):28-32. doi: 10.5980/jpnjurol.113.28.
A 68-year-old female presented with macroscopic hematuria. Cystoscopy revealed a wide-based submucosal mass. Computed tomography revealed a 3.5 × 2.5-cm solitary mass situated from the trigone to the left lateral bladder wall and the left hydroureter and hydronephrosis. T2-weighted magnetic resonance imaging (MRI) revealed low intensity, and diffusion-weighed MRI showed increased diffusion without invasion. The bladder tumor was immediately resected transurethrally. Histological diagnosis of the tissue obtained by transurethral resection was extranodal marginal zone B cell lymphoma of MALT. Positron emission tomography-CT showed no lesions other than the bladder tumor. The patient was diagnosed with stage-IE lymphoma of the bladder (Ann Arbor classification). Radiotherapy was performed at the bladder and pelvis (30 Gy) with six courses of rituximab (375 mg/m). No local or distant recurrence after a 48-month follow-up was noted.
一名68岁女性出现肉眼血尿。膀胱镜检查发现一个基底较宽的黏膜下肿块。计算机断层扫描显示一个3.5×2.5厘米的孤立肿块，位于膀胱三角区至左侧膀胱壁，伴有左侧输尿管积水和肾盂积水。T2加权磁共振成像（MRI）显示低信号强度，扩散加权MRI显示扩散增加但无浸润。膀胱肿瘤立即经尿道切除。经尿道切除组织的组织学诊断为黏膜相关淋巴组织边缘区B细胞淋巴瘤。正电子发射断层扫描-CT显示除膀胱肿瘤外无其他病变。该患者被诊断为膀胱IE期淋巴瘤（Ann Arbor分期）。对膀胱和骨盆进行了放疗（30 Gy），并给予六个疗程的利妥昔单抗（375 mg/m²）治疗。48个月随访后未发现局部或远处复发。
