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肩部人工关节感染:近期文献综述

Prosthetic joint infections of the shoulder: A review of the recent literature.

作者信息

Faria Giles, Flood Catherine, Muhammed Abdul Rasheed, Narang Ashish, Masood Qazi, Bakti Nik, Singh Bijayendra

机构信息

Darent Valley Hospital, Darenth Wood Rd, Dartford, Kent, DA2 8DA, United Kingdom.

Medway Maritime Hospital, Windmill Road, Gillingham, Kent, ME7 5NY, United Kingdom.

出版信息

J Orthop. 2022 Dec 21;36:106-113. doi: 10.1016/j.jor.2022.12.011. eCollection 2023 Feb.

Abstract

INTRODUCTION

Shoulder arthroplasty is a common treatment for shoulder arthritis. Prosthetic joint infection of the shoulder (PJIS) is a debilitating complication to the patient and the healthcare system. Incidence of infection is 0.98-5% for primary arthroplasty. The mean hospital cost for two-stage revision was approximately $35,824. The aim of this paper is to review the recent literature and collate the latest evidence to aid diagnosis and treatment of this serious complication.

METHODS

A literature review was performed using PubMed and Google Scholar databases. A search strategy was adopted using the keywords: 'infection' AND 'shoulder arthroplasty' OR 'total shoulder arthroplasty'OR 'TSA' OR 'reverse shoulder arthroplasty' OR 'RSA' OR 'rTSA'. This initial search resulted in 349 articles. A PRISMA flowchart process was followed. Duplicates were removed, screening was performed and the resulting full texts were analysed and further excluded, leaving 46 articles suitable for inclusion. A PICO search strategy was also used.

RESULTS AND INTERPRETATION

Risk factors for PJIS include procedure type, trauma indications and patient factors.The organism commonly isolated is Cutebacterium acnes, which makes diagnosis challenging due to its indolent nature. Investigations include biochemical tests, synovial aspirate, tissue cultures and radiological examinations.Treatment depends on the depth of the infection and the patient requirements. Medical treatment with antibiotics to local debridement, cement spacer and revision arthroplasty have all been described in the literature. A multidisciplinary decision is made on the microbiological evidence and patient factors.

CONCLUSION

PJIS is a rare but potentially devastating complication of shoulder arthroplasty and diagnosis is often challenging. There has been much research performed recently, providing more evidence on how to optimise management.

摘要

引言

肩关节置换术是治疗肩关节关节炎的常用方法。肩关节假体关节感染(PJIS)对患者和医疗系统而言是一种使人衰弱的并发症。初次置换术的感染发生率为0.98%至5%。两阶段翻修的平均住院费用约为35,824美元。本文旨在回顾近期文献并整理最新证据,以辅助诊断和治疗这一严重并发症。

方法

使用PubMed和谷歌学术数据库进行文献综述。采用搜索策略,关键词为:“感染”与“肩关节置换术”或“全肩关节置换术”或“TSA”或“反肩关节置换术”或“RSA”或“rTSA”。初步搜索得到349篇文章。遵循PRISMA流程图流程。去除重复项,进行筛选,对所得全文进行分析并进一步排除,最终留下46篇适合纳入的文章。还使用了PICO搜索策略。

结果与解读

PJIS的危险因素包括手术类型、创伤指征和患者因素。最常分离出的病原体是痤疮丙酸杆菌,因其生长缓慢的特性,使得诊断具有挑战性。检查包括生化检测、关节液抽吸、组织培养和影像学检查。治疗取决于感染的深度和患者的需求。文献中已描述了从抗生素药物治疗到局部清创、骨水泥间隔器和翻修关节成形术等各种治疗方法。根据微生物学证据和患者因素做出多学科决策。

结论

PJIS是肩关节置换术一种罕见但可能具有毁灭性的并发症,诊断往往具有挑战性。最近进行了大量研究,为如何优化管理提供了更多证据。

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本文引用的文献

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Vancomycin is effective in preventing Cutibacterium acnes growth in a mimetic shoulder arthroplasty.
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