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使用跑步机运动负荷超声心动图对左侧心脏瓣膜狭窄孕妇进行孕前咨询:初步报告。

Preconception consultation using treadmill exercise stress echocardiography for pregnant women with the left-sided heart valve stenosis: A preliminary report.

作者信息

Mohammadi Nasibeh, Shojaeifard Maryam, Kashfi Fahimeh, Larti Farnoosh, Chenaghlou Maryam, Rezaei Yousef, Samiei Niloufar

机构信息

Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Echocardiography Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

出版信息

North Clin Istanb. 2022 Nov 28;9(6):550-556. doi: 10.14744/nci.2021.67809. eCollection 2022.


DOI:10.14744/nci.2021.67809
PMID:36685622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9833388/
Abstract

OBJECTIVE: Pregnancy can increase gradients across the heart valves and consequently deteriorates maternal and fetoneonatal conditions. Hence, pregnancy during heart valve diseases can be challenging and we need to risk stratify patients before conception. We tried to assess the role of preconception consultation using treadmill stress echocardiography (TSE) testing for identifying pregnancy outcomes in women with mitral valve stenosis (MS) or aortic valve stenosis (AS). METHODS: Pregnant patients with a diagnosis of MS or AS were evaluated from January 2015 to December 2018. First group included patients undergoing the TSE testing and they were permitted to get pregnant if they met pre-defined criteria. Second group comprised women who did not undergo TSE testing. Maternal and fetoneonatal outcomes were also recorded. RESULTS: A total of 29 and 18 patients with MS and AS, respectively, were recruited. Among MS patients, individuals without TSE had more functional deterioration (11.1% vs. 35%) and more fetoneonatal events (FNE) (22.2% vs. 55%) compared with those undergoing TSE. The rates of maternal events and mitral valvuloplasty during pregnancy were significantly higher in patients without TSE compared with those undergoing TSE (p=0.015 and p=0.042, respectively). Among AS patients, maternal and FNE were higher in patients without TSE compared with those undergoing TSE, but those were comparable. CONCLUSION: Pregnant patients with the left-sided valvular stenosis who received preconception TSE testing had better outcomes compared with those who did not undergo preconception consultation. This underscores the utility of stress echocardiography in the risk stratification of pregnancies.

摘要

目的:妊娠会增加心脏瓣膜两侧的压力阶差,进而使母婴及胎儿-新生儿状况恶化。因此,患有心脏瓣膜疾病时妊娠可能具有挑战性,我们需要在受孕前对患者进行风险分层。我们试图评估采用平板运动负荷超声心动图(TSE)检查进行孕前咨询在识别二尖瓣狭窄(MS)或主动脉瓣狭窄(AS)女性妊娠结局中的作用。 方法:对2015年1月至2018年12月期间诊断为MS或AS的妊娠患者进行评估。第一组包括接受TSE检查的患者,若符合预定义标准则允许其怀孕。第二组包括未接受TSE检查的女性。同时记录母婴及胎儿-新生儿结局。 结果:共招募了29例MS患者和18例AS患者。在MS患者中,与接受TSE检查的患者相比,未接受TSE检查的患者功能恶化更多(11.1%对35%),胎儿-新生儿事件(FNE)更多(22.2%对55%)。未接受TSE检查的患者孕期母体事件和二尖瓣成形术的发生率显著高于接受TSE检查的患者(分别为p=0.015和p=0.042)。在AS患者中,未接受TSE检查的患者母体事件和FNE高于接受TSE检查的患者,但两者具有可比性。 结论:与未进行孕前咨询的患者相比,接受孕前TSE检查的左侧瓣膜狭窄妊娠患者结局更好。这强调了负荷超声心动图在妊娠风险分层中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a45/9833388/d0afb8c767bc/NCI-9-550-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a45/9833388/f2f9864341c1/NCI-9-550-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a45/9833388/d0afb8c767bc/NCI-9-550-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a45/9833388/f2f9864341c1/NCI-9-550-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a45/9833388/d0afb8c767bc/NCI-9-550-g002.jpg

相似文献

[1]
Preconception consultation using treadmill exercise stress echocardiography for pregnant women with the left-sided heart valve stenosis: A preliminary report.

North Clin Istanb. 2022-11-28

[2]
Echocardiographic Evaluation of Hemodynamic Changes in Left-Sided Heart Valves in Pregnant Women With Valvular Heart Disease.

Am J Cardiol. 2016-10-1

[3]
Clinical and echocardiographic assessment of pregnant women with valvular heart diseases--maternal and fetal outcome.

Int J Cardiol. 2004-3

[4]
Doppler gradients, valve area and ventricular function in pregnant women with aortic or pulmonary valve disease: Left versus right.

Int J Cardiol. 2020-5-1

[5]
[The best of valvular heart disease in 2006].

Arch Mal Coeur Vaiss. 2007-1

[6]
Immediate Outcome of Balloon Mitral Valvuloplasty with JOMIVA Balloon during Pregnancy.

J Clin Diagn Res. 2017-2

[7]
Stress echocardiography beyond coronary artery disease.

Eur Heart J. 1997-6

[8]
Balloon mitral valvuloplasty during pregnancy--our experience.

Rev Port Cardiol. 2002-12

[9]
Impact of moderate to severe mitral stenosis in patients undergoing transcatheter aortic valve replacement.

Int J Cardiol. 2019-3-28

[10]
Update on Valvular Heart Disease in Pregnancy.

Curr Treat Options Cardiovasc Med. 2017-9

本文引用的文献

[1]
Characteristics and Outcomes in a Contemporary Group of Patients With Suspected Significant Mitral Stenosis Undergoing Treadmill Stress Echocardiography.

Circ Cardiovasc Imaging. 2019-6-17

[2]
2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy.

Eur Heart J. 2018-9-7

[3]
2017 ESC/EACTS Guidelines for the management of valvular heart disease.

Eur Heart J. 2017-9-21

[4]
The Role of Stress Echocardiography in Valvular Heart Disease: A Current Appraisal.

Cardiology. 2017

[5]
2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

J Am Coll Cardiol. 2017-7-11

[6]
Risk of Pregnancy in Moderate and Severe Aortic Stenosis: From the Multinational ROPAC Registry.

J Am Coll Cardiol. 2016-10-18

[7]
Echocardiographic Evaluation of Hemodynamic Changes in Left-Sided Heart Valves in Pregnant Women With Valvular Heart Disease.

Am J Cardiol. 2016-10-1

[8]
Predictors of Long-Term Outcomes in Asymptomatic Patients With Severe Aortic Stenosis and Preserved Left Ventricular Systolic Function Undergoing Exercise Echocardiography.

Circ Cardiovasc Imaging. 2016-7

[9]
Pregnancy complicated by valvular heart disease: an update.

J Am Heart Assoc. 2014-6-5

[10]
2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

J Am Coll Cardiol. 2014-6-10

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