袖状胃切除术或Roux-en-Y胃旁路术后的糖尿病缓解率;应用个体化代谢手术评分评估韩国患者
Diabetes Remission Rate after Sleeve Gastrectomy or Roux-en-Y Gastric Bypass; Utilizing Individualized Metabolic Surgery Score for Korean Patients.
作者信息
Park Dae Geun, Chung Yoona, Kim Sang Hyun, Kim Yong Jin
机构信息
Bariatric and Metabolic Surgery Center, H+ Yangji Hospital, Seoul, Korea.
Department of Surgery, Soonchunhyang University Seoul Hospital, Seoul, Korea.
出版信息
J Metab Bariatr Surg. 2020 Jun;9(1):13-18. doi: 10.17476/jmbs.2020.9.1.13. Epub 2020 Jun 30.
PURPOSE
The purpose of this study is to evaluate the usefulness of individualized metabolic surgery score for Korean patients in determining bariatric surgical procedures.
MATERIALS AND METHODS
A total of 135 patients with type 2 diabetes mellitus who underwent sleeve gastrectomy (n=19) or Roux-en-Y gastric bypass (n=116) at our institute with a 1-year follow up were analyzed for the predictive power of diabetes remission using the individualized metabolic surgery scoring system.
RESULTS
At the postoperative follow-up of 1 year, the remission of type 2 diabetes mellitus (HbA<6.5%, off medications) was achieved in 88 (65.2%) patients. The remission rates showed no significant differences between patients who underwent sleeve gastrectomy and Roux-en-Y gastric bypass (63.2% versus 65.5%; P=0.84), regardless of the severity of type 2 diabetes mellitus. Although there was no statistically significant difference in the remission rate according to the bariatric surgery procedures (P>0.99 in mild, P=0.11 in moderate, P>0.99 in severe IMS score), remission rates were higher in moderate severity patients who underwent Roux-en-Y gastric bypass than in those who underwent sleeve gastrectomy (69.7% versus 37.5%).
CONCLUSION
The remission rates after bariatric surgery procedures were similar to that of the previously reported study. Despite the limitations of our data, the individualized metabolic surgery score can be used as a complement to other scoring systems in Korean patients.
目的
本研究旨在评估个体化代谢手术评分对韩国患者在确定减肥手术方式时的有用性。
材料与方法
对在我院接受袖状胃切除术(n = 19)或 Roux - Y 胃旁路术(n = 116)并进行了 1 年随访的 135 例 2 型糖尿病患者,使用个体化代谢手术评分系统分析其糖尿病缓解的预测能力。
结果
术后 1 年随访时,88 例(65.2%)患者实现了 2 型糖尿病缓解(糖化血红蛋白<6.5%,停用药物)。无论 2 型糖尿病的严重程度如何,接受袖状胃切除术和 Roux - Y 胃旁路术的患者缓解率无显著差异(63.2%对 65.5%;P = 0.84)。尽管根据减肥手术方式缓解率无统计学显著差异(轻度时 P>0.99,中度时 P = 0.11,重度个体化代谢手术评分时 P>0.99),但接受 Roux - Y 胃旁路术的中度严重程度患者的缓解率高于接受袖状胃切除术的患者(69.7%对 37.5%)。
结论
减肥手术后的缓解率与先前报道的研究相似。尽管我们的数据存在局限性,但个体化代谢手术评分可作为韩国患者其他评分系统的补充。
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