Ficagna Cassio Antônio, Galli Gabriela Miotto, Zatti Emerson, Sponchiado Bruno Milhoreto, Cecere Bruno Giorgio de Oliveira, Deolindo Guilherme L, Tarasconi Lara, Horn Vitor W, Mendes Ricardo E, Bissacotti Bianca F, Schetinger Maria Rosa Chitolina, Boiago Marcel Manente, da Silva Aleksandro S
Department of Animal Science, Universidade do Estado de Santa Catarina (UDESC), Florianópolis, Brazil.
Graduate Program in Animal Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Arch Anim Nutr. 2022 Jun-Dec;76(3-6):191-204. doi: 10.1080/1745039X.2022.2162796. Epub 2023 Jan 23.
This study aimed to determine whether butyric acid glycerides can replace conventional growth promoters, favour intestinal health, and improve performance. A total of 420 birds were used, divided into four groups with seven repetitions per group ( = 15), as follows: NC, negative control (no promoter); PC, positive control (basal diet + enramycin + salinomycin); MDT-BUT, a diet supplemented with mono-, di-, and triglycerides of butyric acid; TRI-BUT, a diet supplemented with tributyrin of butyric acid glycerides. Productive performance was measured on days 1, 21, 35, and 42. Excreta were collected for counting and coliforms on days 21 and 42. Blood samples were collected at 42 days of age to analyse oxidant/antioxidant status, and the intestine was removed for intestinal morphometry. From 1 to 42 days, there was greater body weight, weight gain, and feed conversion in the PC, MDT-BUT, and TRI-BUT groups than in the NC group; the production efficiency index was 21.10% higher in all groups than in the NC group ( = 0.001). At 21 days, there were lower counts of 86.8% in the TRI-BUT and 99.7% in PC groups than in the NC and MDT-BUT groups ( < 0.001), while at 42 days, lower counts were found in the PC, MDT-BUT, and TRI-BUT groups than the NC group ( < 0.001). There were lower total protein and globulin levels in the MDT-BUT and TRI-BUT groups than in the NC group ( = 0.001). Cholesterol levels were lower in the TRI-BUT group, followed by MDT-BUT and PC groups, than in the NC group ( = 0.001), while lower triglyceride levels were found in the TRI-BUT group than in the NC and PC groups ( = 0.001). There were lower levels of lipid peroxidation and reactive oxygen species in the TRI-BUT group, followed by the PC group than the NC group ( < 0.001); on the other hand, there were higher protein thiol levels in the TRI-BUT group than the NC group ( = 0.041). The villus:crypt ratio increase was 79.4% in the TRI-BUT group, followed by the 45.1% PC and 19.8% MDT-BUT groups than the NC ( < 0.001). These findings suggest that adding butyric acid confers antimicrobial and antioxidant activity and improves birds' production efficiency, intestinal health, and metabolism. Butyric acid glycerides are an effective alternative to conventional growth promoters.
本研究旨在确定丁酸甘油酯是否能够替代传统生长促进剂、有利于肠道健康并提高生产性能。总共使用了420只鸡，分为四组，每组七个重复（每组n = 15），分组如下：NC，阴性对照（无生长促进剂）；PC，阳性对照（基础日粮+恩拉霉素+盐霉素）；MDT - BUT，添加丁酸单酯、二酯和三酯的日粮；TRI - BUT，添加丁酸甘油酯中三丁酸甘油酯的日粮。在第1、21、35和42天测定生产性能。在第21天和第42天收集排泄物以计数大肠杆菌和总大肠菌群。在42日龄时采集血样以分析氧化/抗氧化状态，并取出肠道进行肠道形态测定。从第1天到第42天，PC组、MDT - BUT组和TRI - BUT组的体重、体重增加和饲料转化率均高于NC组；所有组的生产效率指数均比NC组高21.10%（P = 0.001）。在第21天，TRI - BUT组的大肠杆菌计数比NC组和MDT - BUT组分别低86.8%，PC组低99.7%（P < 0.001），而在第42天，PC组、MDT - BUT组和TRI - BUT组的大肠杆菌计数均低于NC组（P < 0.001）。MDT - BUT组和TRI - BUT组的总蛋白和球蛋白水平低于NC组（P = 0.001）。TRI - BUT组的胆固醇水平低于NC组，其次是MDT - BUT组和PC组（P = 0.001），而TRI - BUT组的甘油三酯水平低于NC组和PC组（P = 0.001）。TRI - BUT组的脂质过氧化和活性氧水平低于NC组，其次是PC组（P < 0.001）；另一方面，TRI - BUT组的蛋白质巯基水平高于NC组（P = 0.041）。TRI - BUT组的绒毛：隐窝比值增加了79.4%，其次是PC组增加了45.1%，MDT - BUT组增加了19.8%，均高于NC组（P < 0.001）。这些发现表明，添加丁酸具有抗菌和抗氧化活性，并能提高鸡的生产效率、肠道健康和新陈代谢。丁酸甘油酯是传统生长促进剂的有效替代品。
Zotero 插件