Department of Pediatric Surgery, Ege University Faculty of Medicine, Bornova, 35100, Izmir, Turkey.
Faculty of Science, Dokuz Eylul University, Izmir, Turkey.
Pediatr Surg Int. 2023 Jan 24;39(1):89. doi: 10.1007/s00383-023-05378-1.
AIM: Hesitations concerning the long-term results of transanal endorectal pull-through (TEPT) due to prolonged anal stretching and resultant stricture and continence problems has been started to be questioned. This meta-analysis intended to compare long-term results between TEPT and transabdominal (TAB) pull-through techniques in the surgical management of Hirschsprung's disease. METHODS: All publications between the years 1998-2021 in the PubMed, Medline, Google Scholar, Cochrane databases were reviewed. Retrospective and prospective comparative studies for TEPT, TAB as well as Laparoscopic-assisted TEPT (LTEPT) were included. Data included age at operation, postoperative constipation, enterocolitis, incontinence, stricture, and soiling rates. RESULTS: Eighteen publications met the inclusion criteria for TAB and TEPT, and six for TEPT and LTEPT. Patients who underwent TEPT had significantly younger operation age than patients with TAB (SMD - 1.02, 95%Cl - 1.85 to - 0.18, p: 0.0168). Postoperative constipation (OR 0.39, 95% Cl 0.25-0.61 p < 0.0001) and enterocolitis (OR 0.65, 95% Cl 0.46-0.90, p: 0.0108) rates were significantly lower in TEPT groups. Postoperative incontinence (OR 1.06, 95% Cl 0.56-2.01, p: 0.8468), stricture (OR 1.97, 95% Cl 0.81-4.80, p: 0.1352) and soiling rates were similar between the two groups. Furthermore, when TEPT and LTEPT results were compared, incidence of incontinence (OR 7.01, 95% Cl 0.75-65.33, p: 0.0871), constipation (OR 1.95, 95% Cl 0.70-5.37, p: 0.199), enterocolitis (OR 3.16, 95% Cl 0.34-29.55 p: 0.3137), stricture (OR 1.33, 95% Cl 0.29-6.15, p: 0.7188) and soiling (OR 1.57, 95% Cl 0.57-4.31, p: 0.3778) were similar for both techniques. DISCUSSION: TEPT is superior to TAB in terms of constipation and enterocolitis. Contrary to concerns, postoperative incontinence rates are not statistically different. However, further publications about long-term LTEPT results are necessary for more reliable conclusions.
目的:由于长期的肛门扩张导致的狭窄和控便问题,人们对经肛门直肠内拖出术(TEPT)的长期效果产生了疑虑。本荟萃分析旨在比较先天性巨结肠症的手术治疗中 TEPT 与经腹(TAB)拖出术的长期结果。
方法:对 1998 年至 2021 年间 PubMed、Medline、Google Scholar、Cochrane 数据库中的所有出版物进行了回顾。纳入了 TEPT、TAB 以及腹腔镜辅助 TEPT(LTEPT)的回顾性和前瞻性对照研究。数据包括手术年龄、术后便秘、结肠炎、失禁、狭窄和污染发生率。
结果:18 项研究符合 TAB 和 TEPT 的纳入标准,6 项研究符合 TEPT 和 LTEPT 的纳入标准。与 TAB 组相比,接受 TEPT 的患者手术年龄明显更小(SMD -1.02,95%Cl -1.85 至 -0.18,p=0.0168)。TEPT 组的术后便秘(OR 0.39,95%Cl 0.25-0.61,p<0.0001)和结肠炎(OR 0.65,95%Cl 0.46-0.90,p=0.0108)发生率明显更低。两组术后失禁(OR 1.06,95%Cl 0.56-2.01,p=0.8468)、狭窄(OR 1.97,95%Cl 0.81-4.80,p=0.1352)和污染发生率相似。此外,当比较 TEPT 和 LTEPT 的结果时,失禁(OR 7.01,95%Cl 0.75-65.33,p=0.0871)、便秘(OR 1.95,95%Cl 0.70-5.37,p=0.199)、结肠炎(OR 3.16,95%Cl 0.34-29.55,p=0.3137)、狭窄(OR 1.33,95%Cl 0.29-6.15,p=0.7188)和污染(OR 1.57,95%Cl 0.57-4.31,p=0.3778)的发生率在两种技术之间相似。
讨论:TEPT 在便秘和结肠炎方面优于 TAB。与人们的担忧相反,术后失禁的发生率并无统计学差异。然而,为了得出更可靠的结论,还需要更多关于长期 LTEPT 结果的出版物。
J Laparoendosc Adv Surg Tech A. 2016-1
World J Surg Oncol. 2025-3-28
Wideochir Inne Tech Maloinwazyjne. 2024-11-19
World J Pediatr Surg. 2024-12-31
World J Pediatr Surg. 2024-11-28
World J Pediatr Surg. 2024-8-28
Nat Rev Dis Primers. 2023-10-12
BMC Res Notes. 2018-9-4
Pediatr Surg Int. 2016-8