睾酮治疗对两名跨性别患者偏头痛发作频率和残疾的影响：病例报告。
Effect of testosterone therapy on migraine frequency and disability in two transgender patients: a case report.
机构信息
Centre for Headache, Women's College Hospital, Toronto, Ontario, Canada
Division of Neurology, Adult Neurology Fellowship Program, University of Toronto, Toronto, Ontario, Canada.
出版信息
BMJ Case Rep. 2023 Jan 24;16(1):e251895. doi: 10.1136/bcr-2022-251895.
With an increasing number of patients seeking gender-affirming hormone therapy (GAHT), the clinical impact of testosterone treatments on headache needs to be determined. Our case report looks at the potential effect of testosterone on migraine among transgender patients. We present two transmasculine patients who used masculinising hormone therapy with testosterone. Both patients described their headache as moderate-to-severe pain with features that fulfilled the criteria for chronic migraine without aura. Following GAHT, one patient improved in both frequency and intensity of headache symptoms while the other noted improvement in headache intensity alone. Our report postulates that testosterone therapy may have a positive impact on headaches in individuals participating in GAHT, highlighting the need for further research on the role of testosterone therapy on headache in transmasculine individuals.
随着越来越多的患者寻求性别肯定激素治疗（GAHT），需要确定睾丸激素治疗对头痛的临床影响。我们的病例报告探讨了睾丸激素对跨性别男性患者偏头痛的潜在影响。我们介绍了两名使用雄激素治疗睾丸激素的跨性别男性患者。两名患者均描述其头痛为中度至重度疼痛，其特征符合无先兆偏头痛的标准。GAHT 后，一名患者的头痛发作频率和强度均有所改善，而另一名患者仅头痛强度改善。我们的报告推测，睾丸激素治疗可能对接受 GAHT 的个体的头痛有积极影响，这凸显了进一步研究睾丸激素治疗对跨性别男性个体头痛作用的必要性。
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