All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India.
Dept of Radio-Diagnosis, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India.
PeerJ. 2023 Jan 19;11:e14528. doi: 10.7717/peerj.14528. eCollection 2023.
BACKGROUND: Advanced maternal age is an important parameter associated with increased risk of feto-maternal complications and it is an evolving trend in society for women planning for pregnancy in late ages. However there are no studies done whether advanced maternal age has its effects on expression of growth pattern in the fetus. So this study was done to compare the maternal age with the third trimester fetal biometric parameters. METHODS: This study was done in 100 antenatal women and divided into two groups: Group 1: optimal maternal age group between 21-29 years of age and Group 2: advanced maternal age 30 and above. The pre-pregnant maternal weight, gestational age and third trimester fetal biometrics using ultrasound are noted and compared between the groups. RESULTS: The maternal weight gain between the groups was optimal but the third trimester fetal parameters were significantly less in advanced maternal age. The abdominal circumference in optimal age group and head circumference in advanced maternal age group was closer to calculated estimated date of delivery (EDD) and would be specific in calculating the gestational age. CONCLUSIONS: Though there is no significant difference in maternal weight gain, there are fetal growth restrictions in advanced maternal age group due to which the third trimester fetal parameters are lesser than the optimal age group. Head circumference would be specific in calculating the estimated date of delivery in advanced maternal age group.
背景:高龄产妇是与胎儿-母体并发症风险增加相关的一个重要参数,对于计划晚育的女性来说,这是社会发展的一种趋势。然而,目前尚无研究表明高龄产妇是否会对胎儿的生长模式表达产生影响。因此,本研究旨在比较产妇年龄与孕晚期胎儿生物测量参数之间的关系。
方法:本研究纳入了 100 名孕妇,并将其分为两组:第 1 组:年龄在 21-29 岁之间的最佳产妇年龄组;第 2 组:年龄在 30 岁及以上的高龄产妇组。记录并比较两组孕妇的孕前体重、孕龄和孕晚期胎儿生物测量值。
结果:两组孕妇的体重增加均处于理想水平,但高龄产妇组的孕晚期胎儿参数明显较少。在最佳年龄组中,腹围更接近预产期(EDD)的计算值,而在高龄产妇组中,头围更接近 EDD 的计算值,这有助于更准确地计算孕龄。
结论:尽管产妇体重增加无显著差异,但由于高龄产妇组存在胎儿生长受限,因此其孕晚期胎儿参数小于最佳年龄组。在高龄产妇组中,头围更有助于计算预产期。
Ultrasound Obstet Gynecol. 2020-3
Am J Obstet Gynecol. 2022-7
J Ultrasound Med. 2016-1
Ultrasound Obstet Gynecol. 2019-7-23
Paediatr Perinat Epidemiol. 2015-9
Hypertension. 2015-4-27
Matern Child Health J. 2015-6