Miron A, Toma E A, Enciu O
"Carol Davila" University of Medicine and Pharmacy, General Surgery Department, Emergency University Hospital, Bucharest, Romania.
"Elias" Emergency University Hospital, Bucharest, Romania.
Acta Endocrinol (Buchar). 2022 Jul-Sep;18(3):401-405. doi: 10.4183/aeb.2022.401.
Organ preservation and functional resections are the mainstays of most surgical sub-specialties at the present time. This is even more evident in endocrine surgery, where the product of secretion of these petit organs is of paramount importance. Partial adrenalectomy and cortical sparing techniques have evolved to actually compete with total adrenalectomy, the historical gold standard treatment. Much refined imaging techniques can readily identify smaller adrenal lesions that can be addressed surgically or percutaneously given the indication. The trend towards partial adrenalectomy is straightforward in bilateral disease where steroid replacement can be avoided while for unilateral disease, normal hormonal levels can be obtained. The reviewed publications offer deep insight into the advancement of partial or cortical sparing adrenal procedures from pioneering work to large cohort studies.
器官保存和功能性切除是目前大多数外科亚专业的主要手段。这在内分泌外科更为明显,因为这些小器官的分泌产物至关重要。部分肾上腺切除术和保留皮质技术已经发展到实际上可以与全肾上腺切除术(历史上的金标准治疗方法)相竞争。更加精细的成像技术能够轻易识别出较小的肾上腺病变,根据指征可通过手术或经皮方式进行处理。在双侧疾病中,部分肾上腺切除术的趋势很明确,即可以避免类固醇替代治疗;而对于单侧疾病,则可以维持正常激素水平。所综述的出版物深入洞察了部分或保留皮质的肾上腺手术从开创性工作到大型队列研究的进展。