Permeability and driving force: why is difficult to control glycolytic flux by blocking lactate transporters?
作者信息
Blaszczak Wiktoria, Swietach Pawel
出版信息
Oncotarget. 2023 Jan 26;14:51-52. doi: 10.18632/oncotarget.28351.
Abstract
摘要
相似文献
1
Permeability and driving force: why is difficult to control glycolytic flux by blocking lactate transporters?
Oncotarget. 2023 Jan 26;14:51-52. doi: 10.18632/oncotarget.28351.
2
Autoregulation of H/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production.
Br J Cancer. 2022 Oct;127(7):1365-1377. doi: 10.1038/s41416-022-01910-7. Epub 2022 Jul 15.
3
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.
Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16663-8. doi: 10.1073/pnas.1106123108. Epub 2011 Sep 19.
4
Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis.
Cancer Res. 2014 Feb 1;74(3):908-20. doi: 10.1158/0008-5472.CAN-13-2034. Epub 2013 Nov 27.
5
MCT1 and MCT4 Expression and Lactate Flux Activity Increase During White and Brown Adipogenesis and Impact Adipocyte Metabolism.
Sci Rep. 2017 Oct 12;7(1):13101. doi: 10.1038/s41598-017-13298-z.
6
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.
Cancer Res. 2012 Feb 15;72(4):939-48. doi: 10.1158/0008-5472.CAN-11-2474. Epub 2011 Dec 19.
7
Involvement of monocarboxylate transporter 1 (SLC16A1) in the uptake of l-lactate in human astrocytes.
Life Sci. 2018 Jan 1;192:110-114. doi: 10.1016/j.lfs.2017.10.022. Epub 2017 Nov 14.
8
Role of monocarboxylate transporters in human cancers: state of the art.
J Bioenerg Biomembr. 2012 Feb;44(1):127-39. doi: 10.1007/s10863-012-9428-1.
9
Cardiac energetics in congestive heart failure.
Circulation. 2002 Feb 12;105(6):e44-5.
10
Hyperpolarized [1-C]pyruvate-to-[1-C]lactate conversion is rate-limited by monocarboxylate transporter-1 in the plasma membrane.
Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22378-22389. doi: 10.1073/pnas.2003537117. Epub 2020 Aug 24.
引用本文的文献
1
Exploring monocarboxylate transporter inhibition for cancer treatment.
Explor Target Antitumor Ther. 2024;5(1):135-169. doi: 10.37349/etat.2024.00210. Epub 2024 Feb 23.
本文引用的文献
1
Autoregulation of H/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production.
Br J Cancer. 2022 Oct;127(7):1365-1377. doi: 10.1038/s41416-022-01910-7. Epub 2022 Jul 15.
2
Elevated nuclear localization of glycolytic enzyme TPI1 promotes lung adenocarcinoma and enhances chemoresistance.
Cell Death Dis. 2022 Mar 4;13(3):205. doi: 10.1038/s41419-022-04655-6.
3
Causes, consequences, and therapy of tumors acidosis.
Cancer Metastasis Rev. 2019 Jun;38(1-2):205-222. doi: 10.1007/s10555-019-09792-7.
4
Glucose metabolism is inhibited by caspases upon the induction of apoptosis.
Cell Death Dis. 2014 Sep 4;5(9):e1406. doi: 10.1038/cddis.2014.371.
5
Monocarboxylic acid transport.
Compr Physiol. 2013 Oct;3(4):1611-43. doi: 10.1002/cphy.c130008.
6
THE METABOLISM OF TUMORS IN THE BODY.
J Gen Physiol. 1927 Mar 7;8(6):519-30. doi: 10.1085/jgp.8.6.519.
Zotero 插件