Department of Obstetrics and Gynaecology, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
Department of Paediatrics, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
JNMA J Nepal Med Assoc. 2022 Jul 1;60(251):588-591. doi: 10.31729/jnma.6610.
The incidence of birth defects is 2-3% in the general population but it is increasing. An estimated 303,000 newborns die within 4 weeks of birth every year, worldwide, due to congenital anomalies. The objective of this study was to find out the prevalence of birth defects among newborns in a tertiary care centre.
A descriptive cross-sectional study was done in the Department of Obstetrics and Gynaecology and the Department of Paediatrics from 15 June 2016 and 14 June 2019. Ethical approval was obtained from the Institutional Review Committee (Reference number: 142/077/078-IRC). Data of newborns were collected from the hospital records. Convenience sampling method was used. Point estimate and 99% Confidence Interval were calculated.
Among 32,695 newborns, birth defects were seen in 169 (0.51%) (0.41-0.61, 99% Confidence Interval). The most common birth defect was musculoskeletal defects seen in 60 (35.50%) newborns followed by central nervous system defect seen in 30 (17.75%) newborns.
The prevalence of birth defects among newborns was lower than in other studies done in a similar setting.
birth defect; congenital malformation; prevalence.
一般人群中出生缺陷的发病率为 2-3%,但呈上升趋势。全球每年约有 30.3 万名新生儿在出生后 4 周内因先天异常而死亡。本研究旨在了解三级保健中心新生儿出生缺陷的发生率。
本研究为 2016 年 6 月 15 日至 2019 年 6 月 14 日在妇产科和儿科进行的描述性横断面研究。本研究获得了机构审查委员会的伦理批准(参考编号:142/077/078-IRC)。从医院记录中收集了新生儿的数据。采用方便抽样法。计算了点估计值和 99%置信区间。
在 32695 名新生儿中,有 169 名(0.51%)(0.41-0.61,99%置信区间)出现出生缺陷。最常见的出生缺陷是 60 名(35.50%)新生儿存在肌肉骨骼缺陷,其次是 30 名(17.75%)新生儿存在中枢神经系统缺陷。
与在类似环境中进行的其他研究相比,本研究中新生儿出生缺陷的发生率较低。
出生缺陷;先天性畸形;患病率。