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患者特征及导致细菌性阴道病在初级保健中复发的因素。

Patient characteristics and factors contributing to recurrence of bacterial vaginosis presented in primary care.

机构信息

Department of Primary Care and Community Care, Radboud University Medical Centre, Geert Grooteplein Zuid 21, 6525 EZ, Nijmegen, The Netherlands.

Department of Obstetrics and Gynaecology, Elisabeth-TweeSteden Hospital, PO Box 90151, 5000 LC Tilburg, The Netherlands.

出版信息

Fam Pract. 2023 Dec 22;40(5-6):655-661. doi: 10.1093/fampra/cmad005.

Abstract

BACKGROUND

Bacterial vaginosis (BV) is a common problem in primary care. BV symptoms often have a negative impact on patients' quality of life and may predispose to gynaecological problems. Some patients experience recurring episodes of BV. This study's objective is to identify possible factors that may be associated with BV recurrence and describe the characteristics of these patients and interventions performed by general practitioners.

METHODS

In this retrospective cohort study, we used data from a primary care registration network in the Netherlands in the period 2015-2020. We analysed differences between patients with recurrent BV and patients with a single episode of BV in terms of characteristics and interventions performed by general practitioners.

RESULTS

We found that patients with recently prescribed antibiotics, and a medical history of sexually transmitted infections and/or Candidiasis significantly more often presented with recurrent BV. Patients with recurrent BV had more remote consultations and less in-person consultations than single-episode patients. The reason for encounter was more often a request for medication. Regarding GPs' diagnostic and therapeutic interventions, microbiological tests were more frequently performed in recurrent BV patients. Moreover, most patients in both groups were prescribed oral metronidazole most frequently.

CONCLUSIONS

Our findings might help GPs to better recognise patients at risk of recurrence. GPs could re-evaluate their approach to the diagnosis and treatment of recurrent BV, opting for in-person consultation and using standardised diagnostic criteria and microbiological testing in patients with recurrent complaints. Antibiotic use for other conditions in these patients may lead to new BV episodes.

摘要

背景

细菌性阴道病(BV)是初级保健中的常见问题。BV 症状常对患者的生活质量产生负面影响,并可能导致妇科问题。一些患者反复发作 BV。本研究的目的是确定可能与 BV 复发相关的因素,并描述这些患者的特征以及全科医生所进行的干预措施。

方法

在这项回顾性队列研究中,我们使用了 2015 年至 2020 年荷兰初级保健注册网络的数据。我们分析了反复发作 BV 患者和单次发作 BV 患者在特征和全科医生所进行的干预措施方面的差异。

结果

我们发现,最近开了抗生素的患者、有性传播感染和/或假丝酵母菌病史的患者,更常出现反复发作的 BV。与单次发作的患者相比,反复发作 BV 的患者远程咨询次数更多,而面对面咨询次数更少。就诊的原因更常是开处方。关于全科医生的诊断和治疗干预措施,反复发作 BV 患者更频繁地进行微生物学检查。此外,两组中的大多数患者都最常开口服甲硝唑。

结论

我们的研究结果可能有助于全科医生更好地识别易复发的患者。全科医生可以重新评估他们对反复发作 BV 的诊断和治疗方法,选择面对面咨询,并对有反复发作症状的患者使用标准化的诊断标准和微生物学检查。这些患者因其他疾病使用抗生素可能会引发新的 BV 发作。

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