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同时行结肠切除术和肝射频消融术的安全性。

Safeness of Simultaneous Colonic Resection and Hepatic Radiofrequency Ablation.

机构信息

Assistance Publique-Hôpitaux de Paris (AP-HP), Ambroise-Paré Hospital, Department of Digestive and Oncologic Surgery, Boulogne-Billancourt, France.

Université Paris-Saclay, Université de Versailles-St Quentin en Yvelines (UVSQ), Assistance Publique-Hôpitaux de Paris (AP-HP), Ambroise-Paré Hospital, Department of Radiology, Boulogne-Billancourt, France.

出版信息

JSLS. 2022 Oct-Dec;26(4). doi: 10.4293/JSLS.2022.00070.

Abstract

BACKGROUND AND OBJECTIVES

Previous reports showed an increased risk of infectious complications when liver radiofrequency ablation (RFA) is performed simultaneously to colorectal resection. The aim of this study was to compare early and long-term outcomes of simultaneous versus staged strategy.

METHODS

Data from colorectal cancer liver metastases consecutively treated by surgery of the primary tumor with an associated liver RFA procedure between January 1, 2010 and January 31, 2020. Patients were divided into two groups: RFA performed during colorectal surgery (simultaneous) or in a different moment (staged). Patients were manually matched (1:1) to minimize influence of known covariates.

RESULTS

Seventy-two patients were included. After matching, there was no difference between the two groups in morbidity or mortality. Hospital stay was 2 days shorter in the simultaneous group.

CONCLUSIONS

Early or long-term outcomes were identical between the two strategies. The simultaneous strategy was associated with a shorter duration of hospitalization although not significant. Simultaneous colorectal resection and liver RFA is safe and must be included in surgeons' armamentarium.

摘要

背景与目的

既往研究显示,结直肠切除术同期行肝脏射频消融(RFA)会增加感染并发症风险。本研究旨在比较同期与分期策略的早期和长期结局。

方法

本研究纳入 2010 年 1 月 1 日至 2020 年 1 月 31 日连续接受原发肿瘤手术联合肝 RFA 治疗的结直肠肝转移患者。患者分为两组:RFA 在结直肠手术期间(同期)进行或在不同时间(分期)进行。为了最小化已知混杂因素的影响,患者采用 1:1 手动匹配。

结果

本研究共纳入 72 例患者。匹配后,两组患者的发病率或死亡率无差异。同期组的住院时间缩短了 2 天。

结论

两种策略的早期或长期结局相同。同期策略与较短的住院时间相关,但无统计学意义。结直肠切除术同期行肝脏 RFA 是安全的,应纳入外科医生的治疗手段中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9840214/4c66eb12706c/LS-JSLS220067F001.jpg

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