Cervical Lymph Node Metastasis From Recurrent Glioblastoma Detected by MRI and 2-[18F]FDG PET/CT.
作者信息
Suárez-Piñera Marina, Pudis Michal, Vilariño Noelia, Baixeras Nuria, Torró Carlos Majós
机构信息
From the Deparment of Nuclear Medicine, Institut de Diagnòstic per la Imatge, Hospital Universitari de Bellvitge.
Neuro-Oncology Unit, Hospital Universitari de Bellvitge-ICO L'Hospitalet.
出版信息
Clin Nucl Med. 2023 Mar 1;48(3):e118-e120. doi: 10.1097/RLU.0000000000004546. Epub 2023 Jan 14.
A 53-year-old man diagnosed with recurrent glioblastoma after multimodal treatment on a follow-up brain MRI. Because of a palpable mass in the neck, the patient underwent a whole-body 2-[18F]FDG PET/CT, which revealed hypermetabolic laterocervical confluent lymphadenopathies. A nodal cervical biopsy indicated distant metastases from glioblastoma. Recent studies have confirmed dural meningeal lymphatics, as part of the glymphatic system, which provide clearance of interstitial solutes from the brain parenchyma into cervical lymphatics. Nodal cervical metastases from glioblastoma, using this pathway, are extremely rare and have been almost unthinkable some years ago.
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