John P. and Kathrine G. McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX; Retina Consultants of Texas, Retina Consultants of America, Houston, TX; and Blanton Eye Institute, Houston Methodist Hospital, Houston, TX.
Retina. 2023 May 1;43(5):802-807. doi: 10.1097/IAE.0000000000003718.
To evaluate the association of posterior vitreous opacities (PVOs) on optical coherence tomography with retinal tears identified on examination in patients with acute, symptomatic posterior vitreous detachment (PVD).
Data were retrospectively collected from the medical records of 388 patients with acute, symptomatic PVD between January 1, 2021, and June 30, 2021. Included patients had received a primary diagnosis of PVD and presented with flashes and/or floaters. Optical coherence tomography scans were reviewed by two separate readers for the presence of PVOs. The primary outcome was the presence of retinal tear on fundus photograph and on examination.
Of 388 patients who presented with acute PVD symptoms, 90 (23.2%) were found to have a retinal tear on dilated fundus examination. Among these patients, 78 (86.7%) were found to have PVOs on optical coherence tomography. Statistical analysis demonstrated a significant relationship between the presence of PVOs and retinal tear ( P < 0.01). The sensitivity and specificity of this finding was 86.7% and 72.5%, respectively. Further analysis included area under the curve from receiver operating characteristic curve which was found to be 0.80.
The presence of PVOs on optical coherence tomography is suggestive of a retinal tear in patients with acute, symptomatic PVD.
评估光学相干断层扫描(OCT)中后玻璃体混浊(PVO)与急性症状性后玻璃体脱离(PVD)患者检查中发现的视网膜裂孔之间的关系。
本研究回顾性收集了 2021 年 1 月 1 日至 2021 年 6 月 30 日期间 388 例急性症状性 PVD 患者的病历资料。纳入患者的初步诊断为 PVD,伴有闪光和/或漂浮物。两名独立的读者对 OCT 扫描是否存在 PVO 进行了评估。主要结局是眼底照相和检查中是否存在视网膜裂孔。
在出现急性 PVD 症状的 388 例患者中,有 90 例(23.2%)在散瞳眼底检查中发现视网膜裂孔。在这些患者中,78 例(86.7%)在 OCT 中发现存在 PVO。统计学分析显示,PVO 的存在与视网膜裂孔之间存在显著关系(P<0.01)。该发现的灵敏度和特异性分别为 86.7%和 72.5%。进一步的分析包括受试者工作特征曲线下的面积,发现其为 0.80。
在急性症状性 PVD 患者中,OCT 上存在 PVO 提示存在视网膜裂孔。