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口服塞克硝唑联合阴道硼酸延长疗程治疗持续性 5-硝基咪唑耐药滴虫病的疗效。

Successful Treatment of Persistent 5-Nitroimidazole-Resistant Trichomoniasis With an Extended Course of Oral Secnidazole Plus Intravaginal Boric Acid.

机构信息

From the Section on Infectious Diseases, Wake Forest University School of Medicine, Winston Salem, NC.

Division of Infectious Diseases, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL.

出版信息

Sex Transm Dis. 2023 Apr 1;50(4):243-246. doi: 10.1097/OLQ.0000000000001741. Epub 2022 Nov 29.

Abstract

We describe a case of persistent 5-nitroimidazole-resistant trichomoniasis cured after 14 days of oral secnidazole and intravaginal boric acid. Secnidazole may be an important treatment option for resistant trichomoniasis, particularly in women who fail other regimens, including higher doses of oral metronidazole and tinidazole for longer durations of time.

摘要

我们描述了一例持续 5-硝基咪唑类耐药滴虫病的病例,该病例在接受 14 天口服塞克硝唑和阴道内硼酸治疗后痊愈。塞克硝唑可能是治疗耐药滴虫病的重要选择,特别是对于其他方案失败的女性,包括更高剂量的口服甲硝唑和替硝唑,且治疗时间更长。

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