Bagla Sandeep, Pavidapha Alex, Lerner Jade, Kasimcan Mustafa O, Piechowiak Rachel, Josovitz Kenneth, Marathe Atul, Isaacson Ari, Sajan Abin
Hemorrhoid Centers USA, Falls Church, Virginia.
Hemorrhoid Centers USA, Falls Church, Virginia.
J Vasc Interv Radiol. 2023 May;34(5):745-749. doi: 10.1016/j.jvir.2023.01.023. Epub 2023 Feb 1.
To evaluate the safety and efficacy of outpatient transarterial embolization for symptomatic refractory internal hemorrhoids.
Retrospective analysis of 134 patients who underwent hemorrhoidal artery embolization (HAE) for symptomatic internal hemorrhoids between August 2021 and June 2022 (76 men and 58 women) was performed. The mean age was 54.9 years, with a mean Goligher hemorrhoid grade (HG) of 2.1. Branches of the superior rectal artery (SRA) or middle rectal artery supplying the corpus cavernosum recti were embolized with both spherical particles and microcoils. Standard-of-care evaluations were performed at baseline and the 1 month follow-up, which included hemorrhoid-related pain (HRP) (0-10), hemorrhoid symptoms score (HSS) (5-20), quality of life (QoL) (0-4), French bleeding score (FBS) (0-9), and HG (0-4). Clinical success was defined as improvement of symptoms without additional treatment.
Embolization of at least 1 hemorrhoidal artery was achieved in 133 (99%) of the 134 patients. The mean number of SRA branches embolized per patient was 2.9 ± 1.0. Clinical success was seen in 93% (124 of 134) of patients at the 1-month follow-up, with 10 patients requiring repeat embolization. There were significant improvements in all mean outcomes at 1 month: HSS (11-7.8; P < .01), HRP (4.1-1.3; P < .01), QoL (2.2-0.8; P < .01), FBS (4.4-2.2; P < .01), and HG (2.3-1.2; P < .05). There were no severe adverse events.
HAE is a safe and effective outpatient treatment for refractory symptomatic internal hemorrhoids in the short term.
评估门诊经动脉栓塞术治疗有症状的难治性内痔的安全性和有效性。
对2021年8月至2022年6月期间因有症状的内痔接受痔动脉栓塞术(HAE)的134例患者(76例男性和58例女性)进行回顾性分析。平均年龄为54.9岁,平均戈利格尔痔分级(HG)为2.1级。用球形颗粒和微线圈栓塞供应直肠海绵体的直肠上动脉(SRA)或直肠中动脉分支。在基线和1个月随访时进行标准护理评估,包括痔相关疼痛(HRP)(0 - 10分)、痔症状评分(HSS)(5 - 20分)、生活质量(QoL)(0 - 4分)、法国出血评分(FBS)(0 - 9分)和HG(0 - 4分)。临床成功定义为无需额外治疗症状即得到改善。
134例患者中有133例(99%)实现了至少1条痔动脉的栓塞。每位患者栓塞的SRA分支平均数量为2.9 ± 1.0。在1个月随访时,93%(134例中的124例)的患者临床成功,10例患者需要重复栓塞。1个月时所有平均结果均有显著改善:HSS(从11降至7.8;P < .01)、HRP(从4.1降至1.3;P < .01)、QoL(从2.2降至0.8;P < .01)、FBS(从4.4降至2.2;P < .01)和HG(从2.3降至1.2;P < .05)。未发生严重不良事件。
HAE是短期内治疗难治性有症状内痔的一种安全有效的门诊治疗方法。