Department of Neurology, Sakarya University Faculty of Medicine, Sakarya, Turkey.
Department of Neurology, Edirne Keşan State Hospital, 22800, Keşan/Edirne, Turkey.
Acta Neurol Belg. 2023 Apr;123(2):591-597. doi: 10.1007/s13760-023-02206-0. Epub 2023 Feb 7.
Chorea is a hyperkinetic movement disorder with sudden, irregular, random, dance-like involuntary movements, and ballism is usually one-sided, high-amplitude movements at the proximal of the extremities. In the etiology of acute chorea/hemiballismus, it is necessary to distinguish drugs first and then focus on metabolic causes. The most important etiological causes that may provoke acute/subacute onset chorea/hemiballismus are hypo-hyperglycemia and electrolyte disorders. In this study, we aim to present 19 patients who were admitted to our clinic with movement disorder with acute/subacute onset and diagnosed with chorea/hemiballismus.
The study was completed with 19 patients. Routine biochemistry, HbA1c level, hemogram, sedimentation, CRP, hepatitis panels, detailed infective parameters, HIV, vitamin B12 level, folate levels, and thyroid function tests were studied. All patients underwent neuro-imaging.
16(84.2%) were female and 3(15.8%) were male. The lowest age of the patients was 48 years, the highest age was 89 years, and the mean age was 72.21 years. Thirteen (68.42%) patients had a diagnosis of diabetes mellitus in their history. The blood glucose levels of these patients at the time of admission: the lowest was 99 mg/dl and the highest was 1200 mg/dl. HbA1c values of 11(84.61%) of the 13 patients were also found elevated. Thirteen (68.4%) patients had hemiballismus, 4(21.1%) patients had bilateral choreoathetosis in the four extremities, and 2(10.2%) patients had ballism limited to one upper extremity.
Chorea/hemiballismus is a movement disorder that is rare and can occur due to a wide range of etiologies. The most common metabolic cause is NKHHS.
舞蹈症是一种以突发、不规则、随机、舞蹈样不自主运动为特征的运动障碍，而舞蹈手足徐动症通常是四肢近端的单侧、高振幅运动。在急性舞蹈症/偏侧舞蹈手足徐动症的病因中，首先需要区分药物，然后再关注代谢性病因。可能引发急性/亚急性起病的舞蹈症/偏侧舞蹈手足徐动症的最重要病因是低血糖和电解质紊乱。在本研究中，我们旨在报告 19 例以急性/亚急性起病的运动障碍就诊并诊断为舞蹈症/偏侧舞蹈手足徐动症的患者。
本研究共纳入 19 例患者。检测了常规生化、糖化血红蛋白（HbA1c）水平、血常规、血沉、C 反应蛋白、肝炎标志物、详细的感染参数、HIV、维生素 B12 水平、叶酸水平和甲状腺功能。所有患者均进行了神经影像学检查。
16 例（84.2%）为女性，3 例（15.8%）为男性。患者的最低年龄为 48 岁，最高年龄为 89 岁，平均年龄为 72.21 岁。13 例（68.42%）患者有糖尿病病史。这些患者入院时的血糖水平：最低为 99mg/dl，最高为 1200mg/dl。13 例（84.61%）患者的 HbA1c 值也升高。13 例（68.4%）患者为偏侧舞蹈手足徐动症，4 例（21.1%）患者四肢均有双侧舞蹈徐动症，2 例（10.2%）患者仅一侧上肢有舞蹈手足徐动症。
舞蹈症/偏侧舞蹈手足徐动症是一种罕见的运动障碍，可由多种病因引起。最常见的代谢性病因是 NKHHS。
