卵黄样黄斑营养不良患者的视杆-视锥细胞相互作用
Rod-cone interaction in patients with fundus flavimaculatus.
作者信息
Schneider T, Zrenner E
机构信息
Laboratories of the Max-Planck Institute for Physiological and Clinical Research (Bad Nauheim), University Eye Hospital Munich, Federal Republic of Germany.
出版信息
Br J Ophthalmol. 1987 Oct;71(10):762-5. doi: 10.1136/bjo.71.10.762.
Dark adaptation and the rise of cone flicker threshold (25 Hz) during dark adaptation were measured psychophysically in three patients with fundus flavimaculatus. The dark adaptation curve showed a delayed rod-cone break but a normal final rod threshold in all these patients. However, the rise of cone flicker threshold during dark adaptation was not delayed and also reached a normal final value. This indicates that the delay in rod dark adaptation does not influence the rise of cone flicker threshold during dark adaptation. This finding contrasts with current concepts that the rise of the cone flicker threshold reflects an increasing inhibitory influence of dark adapting rods.
对三名卵黄样黄斑营养不良患者进行了心理物理学测量，以检测暗适应以及暗适应过程中视锥细胞闪烁阈值（25赫兹）的升高情况。暗适应曲线显示，所有这些患者的视杆 - 视锥细胞转折点延迟，但最终视杆细胞阈值正常。然而，暗适应过程中视锥细胞闪烁阈值的升高并未延迟，且最终也达到了正常水平。这表明视杆细胞暗适应的延迟并不影响暗适应过程中视锥细胞闪烁阈值的升高。这一发现与当前的观点形成对比，即视锥细胞闪烁阈值的升高反映了暗适应的视杆细胞抑制作用增强。
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