Illinois College of Optometry, Chicago, Illinois, USA.
Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Ophthalmic Physiol Opt. 2023 Jul;43(4):615-622. doi: 10.1111/opo.13106. Epub 2023 Feb 10.
To determine the effectiveness of the Convergence Insufficiency Symptom Survey (CISS) in evaluating visual symptoms in young adults with convergence excess (CE).
A cross-sectional study was performed based on a population of optometry students. Comprehensive binocular vision tests including cover test, near point of convergence, fusional vergence and accommodative amplitude, were performed. Participants were categorised into three groups: normal binocular vision (NBV), CE and CE + accommodative insufficiency (AI) (i.e., CE + AI). The CISS was administered to each participant. An analysis of variance with Bonferroni correction was performed to compare clinical measures among the three groups. A receiver-operating characteristic (ROC) curve was constructed to evaluate the ability of CISS to differentiate CE from the NBV population.
A total of 181 participants were enrolled, including 96 in the NBV group, 66 in the CE group and 19 in the CE + AI group. A significant difference in CISS score was detected between the three groups (p < 0.001). Post-hoc tests showed significantly higher CISS scores in the CE group (16.7 ± 10.8) and the CE + AI group (19.7 ± 10.9) compared with the NBV group (12.2 ± 7.8) (p = 0.01 and p = 0.005, respectively), with no difference between the CE and the CE + AI groups (p = 0.52). The ROC curve showed the CISS poorly (but significantly) differentiated CE from NBV (area under the curve = 0.62, p = 0.01). The optimal cutoff value for a CISS score to differentiate CE was 16, with sensitivity and specificity of 52% and 72%, respectively.
Young adults with CE had significantly higher CISS scores than those with NBV. Although using the CISS solely for diagnosing CE is not recommended, it can be used to provide a measure of symptoms in individuals identified as having CE based on clinical measurements.
评估集合不足症状调查(CISS)在评估集合过度(CE)的年轻成年人视觉症状方面的有效性。
基于视光学学生群体进行了一项横断面研究。进行了全面的双眼视觉测试,包括遮盖试验、集合近点、融合性集合和调节幅度。将参与者分为三组:正常双眼视觉(NBV)、CE 和 CE+调节不足(AI)(即 CE+AI)。对每位参与者进行 CISS 测试。采用方差分析和 Bonferroni 校正比较三组间临床测量指标。绘制受试者工作特征(ROC)曲线,评估 CISS 区分 CE 与 NBV 人群的能力。
共纳入 181 名参与者,其中 NBV 组 96 名,CE 组 66 名,CE+AI 组 19 名。三组间 CISS 评分差异有统计学意义(p<0.001)。事后检验显示,CE 组(16.7±10.8)和 CE+AI 组(19.7±10.9)的 CISS 评分显著高于 NBV 组(12.2±7.8)(p=0.01 和 p=0.005),CE 组和 CE+AI 组间差异无统计学意义(p=0.52)。ROC 曲线显示 CISS 对 CE 与 NBV 具有较差(但有统计学意义)的区分能力(曲线下面积 0.62,p=0.01)。CISS 评分区分 CE 的最佳截断值为 16,其灵敏度和特异度分别为 52%和 72%。
CE 的年轻成年人 CISS 评分显著高于 NBV。虽然不建议单独使用 CISS 来诊断 CE,但它可以用于根据临床测量结果为被诊断为 CE 的个体提供症状评估。