Burdenko Neurosurgical Center, Moscow, Russia.
Zh Vopr Neirokhir Im N N Burdenko. 2023;87(1):104-110. doi: 10.17116/neiro202387011104.
Trigeminal neuroma (TN) is a benign neoplasm arising from trigeminal nerve sheath. The tumor can grow from any part of the nerve from the root in posterior cranial fossa to peripheral extracranial branches. Symptoms of trigeminal neuroma are variable and usually depend on location and dimensions of tumor. We present a review devoted to the problem of TN. Surgery was the only possible option in patients with TN for a long time. However, radiotherapy became one of the options and sometimes alternative to surgical treatment since the late 1980s. Besides active management of patients with TN, follow-up with regular radiographic control of small asymptomatic tumors also seems to be reasonable. When evaluating treatment outcomes, physicians consider quality of life and return to previous work and activity in addition to resection quality, neurological impairment, relapse-free period and tumor growth control. However, assessment of these indicators after certain treatment is rare. Thus, it is difficult to determine treatment strategy with maximum ratio of effectiveness and quality of life. Therefore, optimization of TN treatment is currently an urgent problem that requires further study.
三叉神经瘤（TN）是一种起源于三叉神经根鞘的良性肿瘤。肿瘤可从颅后窝根部到颅外周围分支的任何神经部位生长。三叉神经瘤的症状多种多样，通常取决于肿瘤的位置和大小。我们对 TN 这一问题进行了综述。长期以来，手术一直是 TN 患者唯一可行的选择。然而，自 20 世纪 80 年代末以来，放射治疗已成为一种治疗选择，有时也是手术治疗的替代方法。除了积极管理 TN 患者外，对无症状小肿瘤进行定期影像学随访似乎也是合理的。在评估治疗结果时，医生除了考虑切除质量、神经损伤、无复发期和肿瘤生长控制外，还会考虑生活质量和恢复以前的工作和活动能力。然而，对某些治疗后这些指标的评估却很少见。因此，很难确定具有最大有效性和生活质量比的治疗策略。因此，优化 TN 的治疗方法目前是一个亟待解决的问题，需要进一步研究。
