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[皮肤-心脏连接的机制]

[Mechanisms of cutaneous-cardial interconnections].

作者信息

Bilibin D P, Shevelev O A, Khodorovich N A, Usanov S S

出版信息

Biull Eksp Biol Med. 1987 Nov;104(11):523-5.

PMID:3676480
Abstract

Using the method of double stimuli, some features of inhibitory influences of conditioning stimulation of cutaneous zones on the afferent transmission from the heart were studied in the experiments on cats. It has been shown that when the interval between testing and conditioning stimuli is from 50 to 150 ms, the cutaneous stimulations effectively block the appearance of evoked potentials in the rostral parts of the cerebral cortex, which were induced by the electrical stimulation of the sinoatrial nodal zone. Bilateral vagotomy completely eliminated this reaction. Stimulation of the peripheral part of the cut vagus also effectively blocked the transmission of the afferent impulses from the heart. It was concluded that inhibitory cutaneo-cardiac effects are determined by the mechanisms of presynaptic inhibition, which develop at the level of intracardiac nervous system.

摘要

采用双刺激法,在猫的实验中研究了皮肤区域条件刺激对心脏传入神经传导的抑制作用的一些特征。结果表明,当测试刺激与条件刺激之间的间隔为50至150毫秒时,皮肤刺激有效地阻断了由窦房结区电刺激诱发的大脑皮质前部诱发电位的出现。双侧迷走神经切断术完全消除了这种反应。刺激切断的迷走神经外周部分也有效地阻断了心脏传入冲动的传导。得出的结论是,抑制性皮肤 - 心脏效应是由心脏内神经系统水平上发生的突触前抑制机制决定的。

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