Vitale Salvatore Giovanni, Della Corte Luigi, Ciebiera Michał, Carugno Josè, Riemma Gaetano, Lasmar Ricardo Bassil, Lasmar Bernardo Portugal, Kahramanoglu Ilker, Urman Bulent, Mikuš Mislav, De Angelis Carlo, Török Péter, Angioni Stefano
Division of Gynecology and Obstetrics, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.
Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy.
Diagnostics (Basel). 2023 Jan 17;13(3):339. doi: 10.3390/diagnostics13030339.
The development of minimally invasive techniques has led to the creation of innovative alternatives in cases where traditional methods are not applicable. In modern gynecology, hysteroscopy has become the gold standard for the evaluation and treatment of intrauterine pathology. Endometrial ablation (EA) is a procedure that uses different types of energy to destroy the endometrium and is currently used as an alternative technique in cases of heavy menstrual bleeding when medical treatment has failed and uterine preservation is desired. The aim of this review was to evaluate the feasibility, safety, and clinical outcomes of hysteroscopic EA as an alternative in patients with abnormal uterine bleeding. A detailed computerized search of the literature was performed in the main electronic databases (MEDLINE, EMBASE, Web of Science, PubMed, and Cochrane Library), from 1994 to June 2022, to evaluate the outcomes in patients with abnormal uterine bleeding (AUB) undergoing EA using hysteroscopic and non-hysteroscopic techniques. Only scientific publications in English were included. Twelve articles on the current use of endometrial ablation were included. Data on patient symptoms, tools used for EA, primary outcomes, and adverse events were recorded. EA should be considered an effective and safe approach in the management of patients with abnormal uterine bleeding caused by benign pathology, in whom medical treatment has failed or is contraindicated. Due to the lack of evidence, it would be interesting to determine whether EA would also have a role in the treatment of women with premalignant lesions, avoiding invasive surgical procedures or medical treatment in those patients for whom hysterectomy or the use of hormonal treatment is contraindicated.
微创技术的发展为传统方法不适用的情况带来了创新的替代方案。在现代妇科领域,宫腔镜检查已成为评估和治疗子宫内病变的金标准。子宫内膜消融术(EA)是一种利用不同类型能量破坏子宫内膜的手术,目前在药物治疗失败且希望保留子宫的月经过多病例中作为一种替代技术使用。本综述的目的是评估宫腔镜下EA作为子宫异常出血患者替代治疗方法的可行性、安全性和临床结局。在1994年至2022年6月期间,在主要电子数据库(MEDLINE、EMBASE、科学网、PubMed和Cochrane图书馆)中进行了详细的计算机文献检索,以评估采用宫腔镜和非宫腔镜技术进行EA的子宫异常出血(AUB)患者的结局。仅纳入英文科学出版物。纳入了12篇关于当前子宫内膜消融术应用的文章。记录了患者症状、用于EA的工具、主要结局和不良事件的数据。对于因良性病变导致子宫异常出血且药物治疗失败或禁忌的患者,EA应被视为一种有效且安全的治疗方法。由于缺乏证据,确定EA在治疗癌前病变女性中是否也有作用,从而避免对那些禁忌子宫切除术或激素治疗的患者进行侵入性手术或药物治疗,将是很有意义的。