典型浅水湖泊长江三角洲淡水食物网中多溴二苯醚的生物积累行为和人体健康风险

Bioaccumulation Behavior and Human Health Risk of Polybrominated Diphenyl Ethers in a Freshwater Food Web of Typical Shallow Lake, Yangtze River Delta.

机构信息

South China Institute of Environmental Sciences, Ministry of Ecology and Environment, The Postgraduate Training Base of Jinzhou Medical University, Guangzhou 510530, China.

State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510530, China.

出版信息

Int J Environ Res Public Health. 2023 Feb 2;20(3):2671. doi: 10.3390/ijerph20032671.

DOI:10.3390/ijerph20032671

PMID:36768037

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9916311/

Abstract

BACKGROUND

Polybrominated diphenyl ethers (PBDEs) have been commonly found in aquatic ecosystems. Many studies have elucidated the bioaccumulation and biomagnification of PBDEs in seas and lakes, yet few have comprehensively evaluated the bioaccumulation, biomagnification, and health risks of PBDEs in shallow lakes, and there is still limited knowledge of the overall effects of biomagnification and the health risks to aquatic organisms.

METHODS

In this study, a total of 154 samples of wild aquatic organism and environmental samples were collected from typical shallow lakes located in the Yangtze River Delta in January 2020. The concentrations of PBDEs were determined by an Agilent 7890 gas chromatograph coupled and an Agilent 5795 mass spectrometer (GC/MS) and the bioaccumulation behavior of PBDEs was evaluated in 23 aquatic organisms collected from typical shallow lakes of the Yangtze River Delta. Furthermore, their effects on human health were evaluated by the estimated daily intake (EDI), noncarcinogenic risk, and carcinogenic risk.

RESULTS

The concentrations of ΣPBDE (defined as the sum of BDE-28, -47, -100, -99, -153, -154, -183, and -209) in biota samples ranged from 2.36 to 85.81 ng/g lipid weight. BDE-209, BDE-153 and BDE-47 were the major PBDE congeners. The factors affecting the concentration of PBDEs in aquatic organisms included dietary habits, species, and the metabolic debromination ability of the PBDE congeners. BDE-209 and BDE-47 were the strongest bioaccumulative PBDE congeners in aquatic organisms. Additionally, except for BDE-99, BDE-153 and BDE-154, the trophic magnification factor (TMF) values of PBDE congeners were significantly higher than 1. Moreover, the log Kow played a significant role in the biomagnification ability of PBDE congeners. The noncarcinogenic risk of PBDE congeners and carcinogenic risk of BDE-209 from aquatic products were lower than the thresholds.

CONCLUSIONS

PBDE congeners were bioaccumulated and biomagnified to varying degrees in aquatic organisms from typical shallow lakes. Both the noncarcinogenic and carcinogenic risks assessment of edible aquatic products indicated that none of the PBDE congeners pose health risks to the localite. This study will provide a basis for a comprehensive assessment of PBDEs in aquatic ecosystems in shallow lakes and for environmental prevention measures for decision-makers.

摘要

背景

多溴二苯醚（PBDEs）在水生生态系统中普遍存在。许多研究已经阐明了 PBDEs 在海洋和湖泊中的生物积累和生物放大作用，但很少有研究全面评估 PBDEs 在浅湖中的生物积累、生物放大作用和健康风险，对于生物放大作用的整体影响和对水生生物的健康风险仍然知之甚少。

方法

本研究于 2020 年 1 月从长江三角洲典型浅湖采集了 154 个野生水生生物和环境样本，采用 Agilent 7890 气相色谱-串联 Agilent 5795 质谱（GC/MS）测定 PBDEs 浓度，评估了 23 种从长江三角洲典型浅湖采集的水生生物中 PBDEs 的生物积累行为。此外，通过估计每日摄入量（EDI）、非致癌风险和致癌风险评估其对人类健康的影响。

结果

生物样本中∑PBDE（定义为 BDE-28、-47、-100、-99、-153、-154、-183 和-209 的总和）浓度范围为 2.36-85.81ng/g 脂重。BDE-209、BDE-153 和 BDE-47 是主要的 PBDE 同系物。影响水生生物中 PBDE 浓度的因素包括饮食习惯、物种和 PBDE 同系物的代谢脱溴能力。BDE-209 和 BDE-47 是水生生物中最强的生物积累 PBDE 同系物。此外，除 BDE-99、BDE-153 和 BDE-154 外，PBDE 同系物的营养放大因子（TMF）值均显著高于 1。此外，log Kow 在 PBDE 同系物的生物放大能力中起着重要作用。来自水产品的 PBDE 同系物的非致癌风险和 BDE-209 的致癌风险均低于阈值。