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对乙酰氨基酚在儿童中的三个W:何人、为何、何种给药方式。

The Three W's of Acetaminophen In Children: Who, Why, and Which Administration Mode.

作者信息

Thibault Céline, Pelletier Élaine, Nguyen Christina, Trottier Evelyne D, Doré-Bergeron Marie-Joëlle, DeKoven Kathryn, Roy Anne-Marie, Piché Nelson, Delisle Jean-Francois, Morin Caroline, Paquette Julie, Kleiber Niina

机构信息

Department of Pharmacology and Physiology (CT, NK), Université de Montreal, Montreal, QC, Canada.

Research Center (CT, NK), CHU Sainte-Justine, Université de Montreal, Montreal, QC, Canada.

出版信息

J Pediatr Pharmacol Ther. 2023;28(1):20-28. doi: 10.5863/1551-6776-28.1.20. Epub 2023 Feb 3.

Abstract

Acetaminophen is one of the oldest medications commonly administered in children. Its efficacy in treating fever and pain is well accepted among clinicians. However, the available evidence supporting the use of acetaminophen's different modes of administration remains relatively scarce and poorly known. This short report summarizes the available evidence and provides a framework to guide clinicians regarding a rational use of acetaminophen in children.

摘要

对乙酰氨基酚是儿童常用的最古老药物之一。其治疗发热和疼痛的疗效在临床医生中已得到广泛认可。然而,支持对乙酰氨基酚不同给药方式使用的现有证据仍然相对较少且鲜为人知。本简短报告总结了现有证据,并提供了一个框架,以指导临床医生合理使用儿童对乙酰氨基酚。

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