Cebotari Diana, Calancea Sergiu, Marrot Jerôme, Guillot Régis, Falaise Clément, Guérineau Vincent, Touboul David, Haouas Mohamed, Gulea Aurelian, Floquet Sébastien
Institut Lavoisier de Versailles, CNRS, UVSQ, Université Paris-Saclay, 45 Av. des Etats-Unis, 78035 Versailles, France.
State University of Moldova, MD-2009 Chisinau, Republic of Moldova.
Dalton Trans. 2023 Mar 7;52(10):3059-3071. doi: 10.1039/d2dt03760b.
[MoV2OS]-based thiosemicarbazone complexes appear as very promising molecules for biological applications due to the intrinsic properties of their components. This paper deals with the synthesis and characterization of six coordination complexes obtained by the reaction of [MoV2OS] clusters with bis-thiosemicarbazone ligands that contain flexible or rigid spacers between the two thiosemicarbazone units. Interestingly, structural characterization by single-crystal X-ray diffraction, MALDI-TOF MS technique and NMR spectroscopy revealed that the nuclearity of the complex is controlled by the nature of the spacer between the thiosemicarbazone units. Binuclear complexes, namely [MoV2OS(L)], are isolated with flexible spacers while tetranuclear complexes [(MoV2OS)(L)] are formed when the bis-thiosemicarbazone ligands are built on rigid spacers.
基于[MoV2OS]的硫代氨基脲配合物由于其组成部分的固有特性，在生物应用中表现为非常有前景的分子。本文涉及通过[MoV2OS]簇与双硫代氨基脲配体反应得到的六种配位配合物的合成与表征，这些双硫代氨基脲配体在两个硫代氨基脲单元之间含有柔性或刚性间隔基。有趣的是，通过单晶X射线衍射、基质辅助激光解吸电离飞行时间质谱技术和核磁共振光谱进行的结构表征表明，配合物的核数由硫代氨基脲单元之间间隔基的性质控制。双核配合物，即[MoV2OS(L)]，是用柔性间隔基分离得到的，而当双硫代氨基脲配体基于刚性间隔基构建时，则形成四核配合物[(MoV2OS)(L)]。
