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激光针灸改善儿童功能性慢性便秘:一项随机对照试验。

Laser acupuncture improving functional chronic constipation in children: a randomized controlled trial.

机构信息

, Cairo, Egypt.

National Institute of Laser Enhanced Sciences (N.I.L.E.S), Cairo University, Cairo, Egypt.

出版信息

Lasers Med Sci. 2023 Feb 15;38(1):72. doi: 10.1007/s10103-023-03727-z.

DOI:10.1007/s10103-023-03727-z
PMID:36790507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9931839/
Abstract

Functional chronic constipation (FCC) is a disorder caused by low fiber consumption, lack of fluid intake, lack of mobility, or side effects of medications. The objective of this study was to compare the effects of laser acupuncture and the commonly used osmotic laxative, lactulose (as the control), both combined with behavioral therapy and dietary modification, on children with FCC in a randomized controlled trial (RCT). Forty children were randomly chosen, aged 5-15 years with FCC, and randomized into two equal groups (gender ratio (50% male; 50% female), mean ± SD weight (24.2 ± 6.27 kg and 25.7 ± 7.47 kg for groups A and B, respectively)). Study group (group A): used laser acupuncture (650 nm), 30 mW, 0.15 cm spot size, 90 s per acupuncture point (ST25, ST36, ST37, BL25, and LI11). Control group (group B): lactulose syrup (1 to 3 mL/kg/day) orally, in divided doses 3 times weekly for 4 weeks, and behavioral training for both groups. Evaluations were conducted before and after the study to assess the efficacy of the therapy. Median value frequency significantly increased in groups A and B post-treatment (4 (6.75-3) and 3 (3.75-2), respectively) compared to pre-treatment (2 (2-1) and 2 (2-0.25), respectively) (p = 0.0001), in favor of group A (p = 0.01). Significant improvement of stool consistency according to Bristol stool scale (BSS) in groups A and B (p = 0.0001), (p = 0.002) respectively in favor of group A (p = 0.03). T-test, Fisher, and Wilcoxon signed rank tests were conducted to compare groups. Non-invasive, painless laser acupuncture therapy can be considered as an alternative therapy for patients with FCC.

摘要

功能性慢性便秘(FCC)是一种由低纤维摄入、液体摄入不足、缺乏运动或药物副作用引起的疾病。本研究的目的是比较激光针灸和常用的渗透性泻药乳果糖(作为对照)联合行为治疗和饮食改变对 FCC 儿童的疗效,这是一项随机对照试验(RCT)。随机选择 40 名年龄在 5-15 岁的 FCC 儿童,并将他们随机分为两组(性别比例(50%男性;50%女性),平均体重±SD(组 A 和组 B 分别为 24.2±6.27kg 和 25.7±7.47kg))。研究组(组 A):使用激光针灸(650nm),30mW,0.15cm 光斑大小,每个穴位 90s(ST25、ST36、ST37、BL25 和 LI11)。对照组(组 B):口服乳果糖糖浆(1-3mL/kg/天),每周 3 次,分 3 次服用,共 4 周,两组均进行行为训练。在研究前后进行评估,以评估治疗的疗效。与治疗前相比,治疗后组 A 和组 B 的中位数频率均显著增加(分别为 4(6.75-3)和 3(3.75-2))(p=0.0001),有利于组 A(p=0.01)。治疗后组 A 和组 B 的粪便稠度均明显改善(Bristol 粪便量表(BSS),p=0.0001),(p=0.002),均有利于组 A(p=0.03)。对两组进行 T 检验、Fisher 检验和 Wilcoxon 符号秩检验。非侵入性、无痛的激光针灸疗法可作为 FCC 患者的替代治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/fbdbb437e980/10103_2023_3727_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/23047f064d10/10103_2023_3727_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/0b466fd4bb67/10103_2023_3727_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/fbdbb437e980/10103_2023_3727_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/23047f064d10/10103_2023_3727_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/3ace2dcca04a/10103_2023_3727_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/f7a0c2b1b7a1/10103_2023_3727_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/0b466fd4bb67/10103_2023_3727_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a27/9931839/fbdbb437e980/10103_2023_3727_Fig5_HTML.jpg

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