Kinkhabwala Corin M, Yuen Erick, Brennan Emily, Cadena Angel, Rizk Habib G
Department of Otolaryngology-Head and Neck Surgery.
MUSC Libraries.
Otol Neurotol. 2023 Apr 1;44(4):e197-e203. doi: 10.1097/MAO.0000000000003832. Epub 2023 Feb 15.
OBJECTIVE: The purpose of this study was to review current treatment options available for mal de debarquement syndrome (MdDS). DATA SOURCES: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Review guidelines, we performed systematic search queries for MdDS-related texts. Documents must have been in the English language, and the time frame was all documents up until May 23, 2022. METHODS: Studies were selected if they were published in a peer-reviewed journal and if one of the primary objectives was the assessment of treatment for MdDS. The quality and validity of all documents were assessed by two independent co-investigators. Conflicts were resolved by a third investigator. RESULTS: One hundred ninety-four unique references were identified and underwent review. Ninety-seven were selected for full-text review, and 32 studies were ultimately included. Data were stratified by treatment methodology for MdDS. The categories used were pharmacologic, physical therapy, and neuromodulating stimulation. CONCLUSIONS: Improvement in patient-reported outcomes is reported with several treatment modalities including specific protocols of vestibular rehabilitation, neuromodulating stimulation, and pharmacologic management with several types of neurotropic drugs.
目的:本研究旨在回顾目前可用于治疗晕动病后综合征(MdDS)的治疗选择。 数据来源:我们依据系统评价与Meta分析扩展版的范围综述指南中的首选报告项目,对与MdDS相关的文本进行了系统检索。文献必须为英文,时间范围是截至2022年5月23日的所有文献。 方法:入选的研究需发表于同行评审期刊,且主要目标之一是评估MdDS的治疗方法。所有文献的质量和有效性由两名独立的共同研究者进行评估。如有分歧,则由第三名研究者解决。 结果:共识别出194篇独特的参考文献并进行了评审。其中97篇被选入全文评审,最终纳入32项研究。数据按MdDS的治疗方法进行分层。使用的类别包括药物治疗、物理治疗和神经调节刺激。 结论:据报告,包括特定的前庭康复方案、神经调节刺激以及使用多种神经营养药物的药物治疗等多种治疗方式,均可改善患者报告的结局。
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